DC10017EED-226
EED226 is a potent, selective, and orally bioavailable embryonic ectoderm development (EED) inhibitor with an IC50 of 22 nM.
View activity & pricesDC Chemicals · Research reagentsDC10017 
DC7311
DC10096
DC8693
DC67710
DC1017
DC9821
DC9402
DC7340
DC8636
DC9950
DC36059
DC9400
DC9401
DC24139
DC8443
DC22536
DC1049
DC7392
DC8657
DC7886
DC7291
DC10148
DC7977
DC10122
DC10468
DC7976
DC9693
DC9459
DCAPI1393
DC8890
DC8649
DC8490
DC8834
DC9669
DC9677
DCAPI1374
DC7455
DC7221
DC8534
DC20016
DC5893
DC7281
DC4129
DC9388
DC7578
DC5188
DC7626
Other Research Tools
1099 products · Page 6 of 23
All small molecule research tools
DC10017DC7311CC-930(Tanzisertib)
Tanzisertib (CC-930) is a potent JNK1/2/3 inhibitor with IC50s of 61/7/6 nM, respectively.
View activity & pricesDC10096GNE-617
GNE-617 is a specific NAMPT inhibitor that inhibits the biochemical activity of NAMPT with an IC50 of 5 nM and exhibits efficacy in xenograft models of cancer.
View activity & pricesDC8693Epiandrosterone
Epiandrosterone is a steroid hormone with weak androgenic activity. Epiandrosterone is naturally produced by the enzyme 5α-reductase from the adrenal hormone DHEA.
View activity & pricesDC67710UNC10225263A
UNC10225263A is a multi-kinase inhibitor, cocktail of UNC10225387B, UNC10225263A and UNC10225761A, promotes stem-cell-like chimeric antigen receptor T cells (CAR T cells).
View activity & pricesDC1017Forskolin
Forskolin is a potent adenylate cyclase activator, with IC50 and EC50 of 41 nM and 0.5 μM for type I adenylyl cyclase, respectively.
View activity & pricesDC9821Ezutromid
Ezutromid is a novel Small utrophin's translation modulator with EC50 of 0.4 uM .In vitro: 1) SMT C1100 induces increased levels of utrophin RNA in human muscle cells.2) Treatment of human DMD cells with SMT C1100 lead…
View activity & pricesDC9402Letermovir(AIC-246)
Letermovir is a novel inhibitor of CMV, which targets the viral terminase complex and remains active against virus resistant to DNA polymerase inhibitors.
View activity & pricesDC7340Wnt-C59
Wnt-C59 (C59) is a highly potent and oral porcupine (PORCN) inhibitor with an IC50 of 74 pM.
View activity & pricesDC8636Varenicline
Varenicline(CP 526555;Champix) is a selective α4β2 nicotinic receptor partial agonist; it stimulates nicotine receptors more weakly than nicotine itself does.Varenicline(CP 526555; Champix; Chantix) is a prescription…
View activity & pricesDC9950SU5614
(Z)-SU5614 is a potent FLT3 inhibitor and selectively induces growth arrest, apoptosis, and cell cycle arrest in Ba/F3 and AML cell lines expressing a constitutively activated FLT3[1].
View activity & pricesDC36059Antibiotic 1037
Toyocamycin (Vengicide) is an adenosine analog produced by Actinomycete, acts as an XBP1 inhibitor, inhibits IRE1α-induced ATP-dependent XBP1 mRNA cleavage, with an IC50 of 80 nM. Toyocamycin (Vengicide) induces…
View activity & pricesDC9400TBB
TBB is a cell-permeable and ATP-competitive CK2 inhibitor with an IC50 of 0.15 μM for rat liver CK2.
View activity & pricesDC9401DMAT(CK2 Inhibitor)
DMAT is a potent and specific CK2 inhibitor with an IC50 value of 130 nM.
View activity & pricesDC24139R(+)-Etomoxir free acid
Etomoxir ((R)-(+)-Etomoxir) is a potent inhibitor of carnitine palmitoyltransferase-I (CPT-1).
View activity & pricesDC8443ESI-09
ESI-09 is a novel noncyclic nucleotide EPAC antagonist with IC50 values of 3.2 and 1.4 μM for EPAC1 and EPAC2, respectively.
View activity & pricesDC22536CFMTI
CFMTI is a potent and selective metabotropic glutamate receptor (mGluR) 1 allosteric antagonist with IC50 of 2.6 nM. The selectivity of CFMTI to mGluR1 over mGluR5 was >2000-fold.
View activity & pricesDC1049Ascomycin (Immunomycin,FK-520)
Ascomycin(Immunomycin, FR-900520, FK520) is an ethyl analog of tacrolimus (FK506) with strong immunosuppressant properties.
View activity & pricesDC7392CW069
CW-069 is an allosteric inhibitor of HSET with an IC50 of 75 μM.
View activity & pricesDC8657R112
R112 is an ATP-competitive inhibitor of Syk kinase with a Ki of 96 nM. R112 inhibits Syk kinase activity with an IC50 of 226 nM.
View activity & pricesDC7886TTNPB
TTNPB is a highly potent RAR agonist. Competitive binding assays using human RARs yield IC50s of α=5.1 nM, β= 4.5 nM, and γ=9.3 nM, respectively.
View activity & pricesDC7291GSK650394
GSK 650394 is a novel SGK inhibitor with IC50 of 62 nM and 103 nM for SGK1 and SGK2 in the SPA assay respectively.
View activity & pricesDC10148SBC-110736
SBC-110736 is a proprotein convertase subtilisin kexin type 9 (PCSK9) inhibitor extracted from patent WO2014150395A1, Figure 1.
View activity & pricesDC7977Nicaraven
Nicaraven is a novel chemically synthesized hydroxyl radical-specific scavenger.
View activity & pricesDC10122Apoptozole
Apoptozole is an inhibitor of the ATPase domain of Hsc70 and Hsp70, with Kds of 0.21 and 0.14 μM, respectively, and can induce apoptosis.
View activity & pricesDC10468Tyrphostin AG-555
AG 555 is an EGFR tyrosine kinase inhibitor.
View activity & pricesDC7976CID 797718
CID-797718 is a compound with unknown details. For the detailed information of CID 797718, the solubility of CID 797718 in water, the solubility of CID 797718 in DMSO, the solubility of CID 797718 in PBS buffer, the…
View activity & pricesDC9693Madrasin
Madrasin is a potent and cell penetrant splicing inhibitor that interferes with the early stages of spliceosome assembly. Madrasin is cytotoxic at higher concentrations, although at lower concentrations it induces cell…
View activity & pricesDC9459SB 415286
SB 415286 is a potent and selective cell permeable inhibitor of GSK-3α, with an IC50 of 77.5 nM, and a Ki of 30.75 nM; SB 415286 is equally effective at inhibiting human GSK-3α and GSK-3β.
View activity & pricesDCAPI1393Nedaplatin (Aqupla)
Nedaplatin is a derivative of cisplatin and DNA damage agent.Target: OthersNedaplatin(NDP) is a derivative of cisplatin which produced less nausea & vomiting and nephrotoxicity. the effect of NDP on the…
View activity & pricesDC8890Imidafenacin
Imidafenacin(KRP-197; ONO-8025) is a potent and selective inhibitor of M3 receptors with Kb of 0.317 nM; less potent for M2 receptors(IC50=4.13 nM).IC50 value: 0.3 nM(M3) [1]in vitro: KRP-197 showed equipotent anti-M2…
View activity & pricesDC86491-Methyl-7-nitroisatoic anhydride
1-methyl-7-nitroisatoic anhydride is a reagent that detects local nucleotide flexibility, for probing 2'-hydroxyl reactivity.
View activity & pricesDC8490SM-164
SM-164 is a cell-permeable Smac mimetic compound. SM-164 binds to XIAP protein containing both the BIR2 and BIR3 domains with an IC50 value of 1.39 nM and functions as an extremely potent antagonist of XIAP.
View activity & pricesDC8834HZ-1157
HZ-1157 inhibits HCV NS3/4A protease with an IC50 of 1.0 μmol/L. HZ-1157 (4a) has a high dengue virus inhibitory activity (EC50 = 0.15 μM) and is a relatively nontoxic (CC50 > 10 μM) dengue antiviral agent[1][2].
View activity & pricesDC9669Fluoroclebopride
Fluoroclebopride is useful chemical for PET image study. [18F]fluoroclebopride had been used for PET imaging of dopamine D2 receptors in monkeys
View activity & pricesDC9677AL 082D06(D-06)
AL 082D06 is a selective, nonsteroidal glucocorticoid receptor (GR) antagonist with Ki of 210 nM.
View activity & pricesDCAPI1374Cyclovirobuxin D(Bebuxine)
Cyclovirobuxine D (CVB-D) is the main active component of the traditional Chinese medicine Buxus microphylla. Cyclovirobuxine D induces autophagy and attenuates the phosphorylation of Akt and mTOR[1]. Cyclovirobuxine D…
View activity & pricesDC7455Lonafarnib
Lonafarnib is an orally bioavailable farnesyl protein transferase (FPTase) inhibitor for H-ras, K-ras and N-ras with IC50 of 1.9 nM, 5.2 nM and 2.8 nM, respectively.
View activity & pricesDC7221P22077
P 22077 is a cell-permeable ubiquitin-specific protease 7 (USP7) inhibitor with an EC50 of 8.01 μM. It also inhibits USP47 with an EC50 of 8.74 μM.
View activity & pricesDC8534α-Amyloid Precursor Protein Modulator(TPPB)
α-Amyloid Precursor Protein Modulator(TPPB) is a cell-permeable benzolactam-derived protein kinase C (PKC) activator with a Ki of 11.9 nM.
View activity & pricesDC20016Naloxegol
Naloxegol (NKTR-118; AZ-13337019) is an opioid-receptor antagonist[1].
View activity & pricesDC5893SCD1 inhibitor
A novel stearoyl-CoA desaturase1 (SCD1) inhibitor.The compound exhibited robust in vivo activity with dose-dependent desaturation index lowering effects. For the detailed information of SCD1 inhibitor, the solubility…
View activity & pricesDC7281SC-514 (GK 01140)
SC-514 is a selective IKK-2 inhibitor (IC50=11.2±4.7 μM), which does not inhibit other IKK isoforms or other serine-threonine and tyrosine kinases.
View activity & pricesDC4129Arranon
Nelarabine (Arranon, 506U78) is a purine nucleoside analog and DNA synthesis inhibitor with IC50 from 0.067-2.15 μM in tumor cells. Nelarabine is a chemotherapy drug used in T-cell acute lymphoblastic leukemia.
View activity & pricesDC9388RS 504393
RS 504393 is a selective CCR2 chemokine receptor antagonist (IC50 values are 89 nM and > 100 μM for inhibition of human recombinant CCR2 and CCR1 receptors respectively).
View activity & pricesDC7578Exatecan (Mesylate)
Exatecan Mesylate is a water soluble topoisomerase I inhibitor, with an IC50 of 2.2 μM (0.975 μg/mL), and can be used in cancer research.
View activity & pricesDC5188Sarecycline(P005672 hydrochloride)
Sarecycline hydrochloride is a narrow-spectrum tetracycline-class antibiotic. Sarecycline hydrochloride possesses anti-inflammatory properties and potent activity against Gram-positive bacteria, including activity…
View activity & pricesDC7626GS9973（Entospletinib）
Entospletinib (GS-9973) is an orally bioavailable, selective?Syk inhibitor with an IC50 of 7.7 nM.
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