DC1078AG-1478 (Tyrphostin AG-1478)
AG-1478 is a selective EGFR tyrosine kinase inhibitor with IC50 of 3 nM.
View activity & pricesDC Chemicals · Research reagentsDC1078 
DC4200
DC60042
DC7627
DC5006
DC8721
DC4187
DCAPI1014
DC8722
DC3109
DC4190
DC5029
DCAPI1177
DC8011
DC8638
DC8838
DC21522
DC7551
DC10542
DC10574
DC12513
DC12624
DC6302
DC1024
DC26141
DC9304
DC9031
DC8870
DC9488
DC8026
DC5023
DCAPI1490
DC22516
DC8187
DC9784
DC4217
DC8855
DC8382
DC8972
DC60225
DC39262
DC22989
DC3112
DC7589
DC10895
DC26154
DC9760
Other Research Tools
1099 products · Page 4 of 23
All small molecule research tools
DC1078DC4200Fulvestrant
Fulvestrant is a potent Estrogen Receptor antagonist with an IC50 of 9.4 nM.
View activity & pricesDC60042YKP-3089
Cenobamate, a sodium channel blocker, enhances GABAergic transmission and has the potential to be a versatile CNS drug.
View activity & pricesDC7627EHT-1864
EHT 1864 selectively inhibits Rac-induced lamellipodia Formation, and specifically reverses cell trans Formation induced by constitutively activated mutants of Rac1 and Tiam1. EHT 1864 strongly impaires oncogenic…
View activity & pricesDC5006XAV-939
XAV-939 is a tankyrase (TNKS) inhibitor and an indirect inhibitor of Wnt/β-catenin signaling, with IC50s of 5 and 2 nM for TNKS1 and TNKS2, respectively.
View activity & pricesDC8721Sirtinol
Sirtinol is a sirtuin inhibitor, with IC50s of 48 μM, 57.7 μM and 131 μM for ySir2, hSIRT2 and hSIRT2, respectively.
View activity & pricesDC4187Docetaxel
Docetaxel is an antineoplastic drug by inhibiting microtubule depolymerization, and attenuating of the effects of bcl-2 and bcl-xL gene expression.
View activity & pricesDCAPI1014Eplerenone
Eplerenone is an aldosterone antagonist with an IC50 of 0.36 μM.Eplerenone is a selective mineralocorticoid receptor antagonist, which has been shown to produce sustained increases in plasma renin and serum…
View activity & pricesDC8722Dimethoxycurcumin(DiMC)
Naturally occurring phytochemicals such as turmeric (curcumin) have been found to inhibit the growth of tumor cells. Dimethoxycurcumin is an analog of curcumin obtained by methylation of both free phenolic groups in…
View activity & pricesDC3109Ipatasertib (GDC-0068)
Ipatasertib (GDC-0068) is a highly selective and ATP-competitive pan-Akt inhibitor with IC50s of 5, 18 and 8 nM for Akt1, Akt2 and Akt3, respectively.
View activity & pricesDC4190Fludarabine phosphate
Fludarabine (phosphate) is an analogue of adenosine and deoxyadenosine, which is able to compete with dATP for incorporation into DNA and inhibit DNA synthesis.
View activity & pricesStructure information available on request
DC7615Capromorelin
Capromorelin Tartrate is an orally active, potent growth hormone secretagogue receptor (GHSR) agonist, with Ki of 7 nM for hGHS-R1a.
View activity & pricesDC5029PERK inhibitor GSK2656157
GSK2656157 is a selective and ATP-competitive inhibitor of protein kinase R (PKR)-like endoplasmic reticulum kinase (PERK) with an IC50 of 0.9 nM.
View activity & pricesDCAPI1177Salubrinal
Salubrinal is a cell-permeable and selective inhibitor of eIF2α dephosphorylation.
View activity & pricesDC8011Radotinib (IY-5511)
Radotinib(IY-5511) is a novel and selective BCR-ABL1 tyrosine kinase inhibitor with IC50 of 34 nM for wild-type BCR-ABL1 kinase.Radotinib is a BCR-ABL1 specific 2nd-generation tyrosine kinase inhibitor. According to…
View activity & pricesDC8638Paclitaxel
Paclitaxel is a potent anticancer medication which can promote microtubule (MT) assembly, inhibit MT depolymerization, and change MT dynamics required for mitosis and cell proliferation.
View activity & pricesDC8838Indirubin
Indirubin(Couroupitine B) is a purple 3,2- bisindole and a stable isomer of indigo isolated from Indigo naturalis (Apiaceae); anti-inflammatory and anticancer activities.IC50 value:Target:in vitro: The activation of…
View activity & pricesDC21522Balixafortide(POL6326)
Balixafortide (POL6326) is a potent, selective, well-tolerated peptidic CXCR4 antagonist with an IC50 < 10 nM. Balixafortide shows 1000-fold selective for CXCR4 than a large panel of receptors including CXCR7.…
View activity & pricesDC7551RG3039(PF-06687859)
RG3039 (PF-06687859) is an orally bioavailable and brain-penetrant DcpS inhibitor with an IC50 of 0.069 nM.
View activity & pricesDC10542KIRA6
KIRA6 allosterically inhibits IRE1α RNase kinase activity with an IC50 of 0.6 µM.
View activity & pricesDC10574CID-25014542
CID-25014542 is novel inhibitor of Raf kinases.
View activity & pricesDC12513RIP1 inhibitor GSK547
GSK547, a highly selective and potent RIP1 inhibitor, inhibits macrophage-mediated adaptive immune tolerance in pancreatic cancer[1].
View activity & pricesDC12624RAS activator compound 1
RAS activator compound 1 is a small molecule RAS activator compound that increases the rate of SOS-catalyzed nucleotide exchange in vitro with EC50 of 14 uM; targets SOS1 induced biphasic modulation of RAS-GTP and ERK…
View activity & pricesDC6302AZD2858
AZD2858 is a potent, orally active GSK-3 inhibitor, with IC50s of 0.9 and 5 nM for GSK-3α and GSK-3β, respectively, used in the research of fracture healing.
View activity & pricesDC1024Afatinib (BIBW2992)
For the detailed information about the solubility of Afatinib (BIBW2992) in water, the solubility of Afatinib (BIBW2992) in DMSO, the solubility of Afatinib (BIBW2992) in PBS buffer, the animal experiment（test） of…
View activity & pricesDC26141TPT-260
TPT-260(TPU260) is a thiophene thiourea derivative with molecule weight 260.00 in free base form; There is no formal name yet, we temporally call this molecule as TPT-260.IC50 value:Target:
View activity & pricesDC9304LY2334737
LY2334737 is an orally available prodrug of gemcitabine which is a nucleoside analog used as chemotherapy.IC50 Value:Target: Nucleoside analogin vitro: Five cell lines that express CES2 responded to LY2334737treatment.…
View activity & pricesDC9031Clodronate disodium
Clodronate disodium is available from DC Chemicals for laboratory research. Contact us for application-specific product information.
View activity & pricesDC8870Eupatilin
Eupatilin, a lipophilic flavonoid isolated from Artemisia species, is a PPARα agonist, and possesses anti-apoptotic, anti-oxidative and anti-inflammatory activities.
View activity & pricesDC9488Cilengitide
Cilengitide is a potent and selective integrin inhibitor for αvβ3 and αvβ5 receptor, with IC50s of 4 and 79 nM, respectively.
View activity & pricesDC8026PFK-015
PFK-015 is an effective inhibitor of PFKFB3 with IC50 of 110 nM (recombinant PFKFB3) and inhibits PFKFB3 activity in cancer cells with IC50 of 20 nM.PFK-015 possesses compelling in vitro properties, has satisfactory PK…
View activity & pricesDC5023Birinapant (TL32711)
Birinapant, a bivalent Smac mimetic, is a potent antagonist for XIAP and cIAP1 with Kds of 45 nM and less than 1 nM, respectively.
View activity & pricesDCAPI1490Anidulafungin
Anidulafungin is a new semisynthetic echinocandin with antifungal potency.
View activity & pricesDC22516Nanvuranlat (JPH203)
JPH203 is a potent and selective L-type amino acid transporter 1 (LAT-1) inhibitor.
View activity & pricesDC8187Ciraparantag(PER977)
Ciraparantag is a thrombin and factor Xa inhibitors as well as to heparin-based anticoagulants through non-covalent hydrogen bonding and charge interactions. It is reported to antagonize the effects of all coagulants…
View activity & pricesDC9784Lu AF21934
Lu AF21934 is a selective and brain-penetrant mGlu4 receptor positive allosteric modulator with an IC50 of 500 nM for human mGlu4.
View activity & pricesDC4217Maraviroc
Maraviroc is a selective CCR5 antagonist with activity against human HIV.
View activity & pricesDC8855Fumagillin
Fumagillin(NSC9168) is a complex biomolecule and used as an antimicrobial agent.Target: AntiparasiticFumagillin is an active amebicide and anti-infective isolated from the fungus Aspergillus fumigatus. Fumagillin does…
View activity & pricesDC8382PF-03084014 (Nirogacestat)
Nirogacestat (PF-3084014) is a reversible, noncompetitive, and selective γ-secretase inhibitor with IC50 of 6.2 nM.
View activity & pricesDC8972Carmustine
Carmustine is an antitumor chemotherapeutic agent, which works by akylating DNA and RNA.
View activity & pricesDC60225AOD-9604
AOD-9604 is a potential anti-obesity peptide based on human growth hormone. AOD9604 was originally developed after research on mice, but subsequent studies in human have shown no efficacy for the potential treatment of…
View activity & pricesDC39262SBP-7455
SBP-7455 is an orally active dual-specific ULK1/2 autophagy inhibitor with improved binding affinity compared with SBI-0206965.
View activity & pricesDC22989BMS-204493
BMS-204493(BMS493) is an inverse pan-retinoic acid receptor (RAR) agonist. BMS493 increases nuclear corepressor interaction with RARs. BMS493 also could prevent retinoic acid-induced differentiation[1][2].
View activity & pricesDC3112AS-252424
AS-252424 is a potent and selective PI3Kγ inhibitor with an IC50 of 30±10 nM.
View activity & pricesDC7589Eniporide(EMD96785)
Eniporide is a The Na(+)/H(+) exchange inhibitor.
View activity & pricesDC10895E260
E260 is a Fer/FerT kinase inhibitor.
View activity & pricesDC26154LIT927
LIT-927 is a locally and orally active CXCL12 neutraligand with anti-inflammatory effect, with a Ki of 267 nM for CXCL12-TR binding.
View activity & pricesDC9760Dihexa (PNB-0408)
Dihexa is an orally active, blood-brain barrier-permeable angiotensin IV analog; exhibits high affinity binding hepatocyte growth factor (HGF) with a Kd of 65 pM.
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