1099 products · Page 17 of 23
All small molecule research tools
DC5010UNC0646 is a potent and selective G9a inhibitor with IC50 of 6 nM.UNC0646 is a potent and selective inhibitor of the homologous protein lysine methyltransferases, G9a and GLP (IC50 values are 6 nM and 15 nM for G9a and…
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DC7347Cephalosporin C Na salt is used to study the effect of transpeptidase expression, binding, and inhibition on bacterial cell wall mucopeptide synthesis. Cephalosporin C has been used to determine activity during…
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DC6905Linezolid (PNU-100766) is a synthetic antibiotic used for the treatment of serious infections caused by Gram-positive bacteria that are resistant to several other antibiotics.
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DC9753FCCP is an uncoupler of oxidative phosphorylation in mitochondria.
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DC9561Nitisinone(SC0735) is an inhibitor of the enzyme 4-hydroxyphenylpyruvate dioxygenase.Nitisinone is a drug used to slow the effects of hereditary tyrosinemia type 1. Nitisinone reduced urinary HGA levels from an average…
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DC25200PF-1355 is a selective 2-thiouracil mechanism-based MPO inhibitor, used for treatment of vasculitic diseases.
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DC8073Bohemine is a purine analogue and is a synthetic and selective CDK inhibitor with IC50s of 4.6 μM, 83 μM, and 2.7 μM for Cdk2/cyclin E, Cdk2/cyclin A, and Cdk9/cyclin T1, respectively. Bohemine also inhibits ERK2 with…
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DC8383Dp44mT is an iron chelator with selective anticancer activity.
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DC6912Etofibrate is the ethandiol-1,2 diester of the nicotinic and clofibric acids. Etofibrate has been shown to be a potent hypolipidemic agent in animal and human.
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DC7278SB-505124 is a selective inhibitor of TGFβR with IC50 of 129 nM and 47 nM for ALK4, ALK5, respectively, and it does not inhibits ALK1, 2, 3, or 6 but ALK7.
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DC26003Novel PDZ binding kinase (PBK) inhibitor.
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DC7632BTB06584 is an IF1-dependent selective inhibitor of the mitochondrial F1Fo-ATPase.
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DCAPI1391Ranolazine is an antianginal medication.Target: Sodium ChannelRanolazine is believed to have its effects via altering the transcellular late sodium current. It affects the sodium-dependent calcium channels during…
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DCAPI1037For the detailed information of Gadodiamide (Omniscan), the solubility of Gadodiamide (Omniscan) in water, the solubility of Gadodiamide (Omniscan) in DMSO, the solubility of Gadodiamide (Omniscan) in PBS buffer, the…
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DC9529Glutaminase C-IN-1 (968) is an allosteric inhibitor of Glutaminase C that inhibits cancer cell growth without affecting their normal cellular counterparts.
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DC3140Dasatinib monohydrate (BMS-354825 monohydrate) is a highly potent, ATP competitive, orally active dual Src/Bcr-Abl inhibitor with potent antitumor activity. The Ki values of 16 pM and 30 pM for Src and Bcr-Abl,…
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DC8804APD597 is a GPR119 agonist intended for the treatment of type 2 diabetes, with EC50 of 46 nM for hGPR119.
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DC10758LM22B-10 is an activator of TrkB/TrkC neurotrophin receptor, and can induce TrkB, TrkC, AKT and ERK activation in vitro and in vivo.
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DC22069DB818 (DB-818, DB 818) is a small molecule inhibitor of HOXA9/DNA interaction through binding as minor groove DNA ligand on the HOXA9 cognate sequence; directly bind to HOXA9-cognate sequence with Kd value of 4.6 nM…
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DC7619Tazarotenic acid is the metabolite of Tazarotene. Tazarotenic acid binding to retinoic acid receptors (RARs) is the probable molecular target of retinoid action. Tazarotenic acid has the potential for the research of…
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DC50027ENMD-2076 Tartrate is a multi-targeted kinase inhibitor with IC50s of 1.86, 14, 58.2, 15.9, 92.7, 70.8, 56.4 nM for Aurora A, Flt3, KDR/VEGFR2, Flt4/VEGFR3, FGFR1, FGFR2, Src, PDGFRα, respectively.
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DCAPI1202Vecuronium bromide is a nondepolarizing neuromuscular blocking agent of intermediate duration.
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DC9780Tenofovir dsoproxil is a nucleotide reverse transcriptase inhibitor to treat HIV and chronic Hepatitis B.
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DC106741-EBIO is an Epithelial KCa channel activator. Promotes ESC differentiation into cardiomyocytes.
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DC65642Thymosin beta 4 is a potent regulator of actin polymerization in living cells. Sequence:…
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DC24145An aminoglycoside antibiotic similar in structure to gentamicin B1; blocks polypeptide synthesis by inhibiting the elongation step in both prokaryotic and eukaryotic cells.
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DC10266Nandrolone Decanoate is a mild form of an anabolic steroid.
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DC7703AEBSF is an irreversible inhibitor of serine proteases, such as chymotrypsin, kallikrein, plasmin, thrombin, and trypsin.
View activity & pricesAuristatin E is a cytotoxic tubulin modifier with potent and selective antitumor activity; MMAE analog and cytotoxin in Antibody-drug conjugates.
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DC82103Ensifentrine (RPL-554) is an inhaled first-in-class dual inhibitor of phosphodiesterase 3 (PDE3) and PDE4 with IC50s of 0.4 nM and 1479 nM, respectively. Ensifentrine has bronchoprotective and anti-inflammatory…
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DC7688XMD-17-51 is a potent NUAK1-specific NUAK1 inhibitor
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DC7399Deferitrin (GT-56-252), a desferrithiocin (DFT) analogue, is an orally active trident iron chelator. Deferitrin is used for chronic iron overload due to transfusional therapy. Deferitrin has the potential for…
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DC10752CNDAC hydrochloride is a metabolite of the orally active agent sapacitabine, and a nucleoside analog[1].
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DC9535Brivaracetam(UCB-34714) is a 4-substituted pyrrolidone butanamide as agent with significant antiepileptic activity; high affinity SV2A ligand and also shows an ability to inhibit Na+ channels. in vitro: Brivaracetam…
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DC10687Sematilide hydrochloride (CK-1752 hydrochloride) is a selective IKr channel blocker. Sematilide causes a concentration-dependent inhibition of the delayed rectifier K+ current (IC50=25 μM). Sematilide is a class III…
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DC7204Ezatiostat is a glutathione analog inhibitor of glutathione S-transferase P1-1 (GSTP1-1).
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DCAPI1329Argatroban is a direct, selective thrombin inhibitor.
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DC5908Honokiol is a bioactive, biphenolic phytochemical that possesses potent antioxidative, anti-inflammatory, antiangiogenic, and anticancer activities by targeting a variety of signaling molecules. It inhibits the…
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DC7129GANT 61 is an inhibitor of Gli1 and Gli2 targeting the Hedgehog/GLI pathway.
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DCAPI1425Anastrozole is a potent, highly selective aromatase inhibitor, which inhibits human placental aromatase with an IC50 of 15 nM.
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DC7745Filorexant (MK-6096) is an orally bioavailable potent and selective reversible antagonist of OX1 and OX2 receptor(<3 nM in binding).
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DC6502Cardamonin is a novel antagonist of hTRPA1 cation channel with an IC50 of 454 nM
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DC8398NPS-1034 is a dual inhibitor of AXL and MET with IC50s of 10.3 and 48 nM, respectively.
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DC20267Serotonin hydrochloride is a monoamine neurotransmitter in the CNS and an endogenous 5-HT receptor agonist. Serotonin hydrochloride is also a catechol O-methyltransferase (COMT) inhibitor with a Ki of 44 μM.
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DC7765Skepinone-L is a selective p38 mitogen-activated protein kinase inhibitor. IC50 value:Target: p38MAPKskepinone-L, the first ATP-competitive p38 MAPK inhibitor with excellent in vivo efficacy and selectivity. Therefore,…
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DC91883,3',5-Triiodo-L-thyronine sodium is an active form of thyroid hormone, which binds to β1 thyroid hormone receptor (TRβ1), and activates its activity.
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DC9354Tigecycline is a first-in-class, broad spectrum antibiotic with activity against antibiotic-resistant organisms.Tigecycline is active against a broad range of gram-negative and gram-positive bacterial species including…
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DC22625Rolipram is a selective phosphodiesterases PDE4 inhibitor with IC50s of 3 nM, 130 nM and 240 nM for PDE4A, PDE4B, and PDE4D, respectively.
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