DC7406Dynasore
Dynasore is a cell-permeable dynamin inhibitor with an IC50 of 15 μM.
View activity & pricesDC Chemicals · Research reagentsDC7406 
DC7051
DC8478
DC20023
DC8466
DC41869
DC8062
DC10741
DC60568
DC22537
DC11312
DC10722
DC21786
DC7655
DC8274
DC5167
DC7613
DC21288
DC9835
DC7029
DC12443
DC9287
DC8783
DC10783
DC7368
DC7553
DC21748
DC10397
DC21695
DC7743
DC8835
DC23161
DC30002
DC23825
DC9536
DC22604
DC10905
DC5172
DC33598
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1099 products · Page 8 of 23
All small molecule research tools
DC7406DC7051AG-18
Tyrphostin 23 (Tyrphostin A23) is an EGFR inhibitor with an IC50 and Kiof 35 and 11 μM, respectively.
View activity & pricesDC8478M 344
M344 (D 237) is an inhibitor of histone deacetylase (IC50=100 nM) and an inducer of terminal cell fifferentiation.
View activity & pricesDC20023TP0463518
TP0463518 is a potent hypoxia-inducible factor prolyl hydroxylases (PHDs) inhibitor with a Ki value of 5.3 nM for human PHD2. TP0463518 also inhibits human PHD1/PHD3 with IC50s of 18 and 63 nM as well as monkey PHD2…
View activity & pricesDC8466CPI-169 (racemate）
CPI-169 racemate is the racemate form of CPI-169, which is a novel and potent EZH2 inhibitor with IC50 <1 nM(inhibition of the catalytic activity of PRC2); decreases cellular levels of H3K27me3 with an EC50 of 70 nM,…
View activity & pricesDC41869PAMP-12(human, porcine)
PAMP-12(human, porcine) is a major component of immunoreactive (ir)-PAMP, is processed from the adrenomedullin precursor, is a potent hypotensive peptide and participates in cardiovascular control.
View activity & pricesDC8062BX517
BX517 is a potent and selective inhibitor of PDK1 with IC50 of 6 nM.
View activity & pricesStructure information available on request
DC11332Degarelix (acetate)
Degarelix is a competitive and reversible gonadotropin-releasing hormone receptor (GnRHR) antagonist.
View activity & pricesStructure information available on request
DC11152BLU-782
ALK2-IN-1 is a activin receptor-like kinase-2 (ALK2) inhibitor extracted from patent WO2017181117A1, Compound 876, has an IC50 of <10 nM[1].
View activity & pricesDC10741HAMNO (NSC111847)
HAMNO is a novel protein interaction inhibitor of replication protein A (RPA).
View activity & pricesDC60568RMC-9805（Zoldonrasib）
RMC-9805 is a first-in-class, mutant-selective, covalent and orally bioavailable KRAS-G12D(ON) inhibitor. RMC-9805 exhibits direct anti-tumor effects and indirectly transformed the TME through inhibition of cancer…
View activity & pricesDC22537SMAP
SMAP (DT-061, DT061) is an orally bioavailable small molecule activator of PP2A, inhibits KRAS-driven tumor growth; acts by binding to the PP2A Aα scaffold subunit to drive conformational changes in PP2A; inhibits the…
View activity & pricesDC11312Xanthine amine congener
Xanthine amine congener (XAC) is a non-selective adenosine receptor antagonist with Kb values of 83, 25, and 15 nM for rat PC12 cells, human platelets that endogenously express adenosine A2A receptors, and rat fat…
View activity & pricesDC10722CGP-71683A
CGP71683 hydrochloride is a competitive neuropeptide Y5 receptor antagonist with a Ki of 1.3 nM, and shows no obvious activity at Y1 receptor (Ki, >4000 nM) and Y2 receptor (Ki, 200 nM) in cell membranes.
View activity & pricesDC21786UU-T02
UU-T02 is a novel potent, selective small-molecule inhibitor of β-catenin/Tcf4 interaction with Ki of 1.36 uM; displays 63-fold and 175-fold selectivity over β-catenin/E-cadherin and β-catenin/APC interactions,…
View activity & pricesDC7655APD668
APD668 is a potent GPR119 agonist with EC50 of 2.7 nM and 33 nM for hGPR119 and ratGPR119 respectively.Chronic treatment withAPD668 showed for the first time that blood glucose and glycated hemoglobin (HbA1c) levels…
View activity & pricesDC8274Dihydroethidium
Dihydroethidium(Hydroethidine; PD-MY 003) is a superoxide indicator; exhibits blue-fluorescence in the cytosol until oxidized, where it intercalates within the cell's DNA, staining its nucleus a bright fluorescent red.
View activity & pricesDC5167Ceritinib(LDK378)
Ceritinib (LDK378) is a potent and specific ALK inhibitor with an IC50 of 0.2 nM.
View activity & pricesDC7613STATTIC
Stattic is a potent inhibitor of STAT3 activation and dimerization.
View activity & pricesDC21288MK-8617
MK-8617 is an orally active pan-inhibitor of hypoxia-inducible factor prolyl hydroxylase 1-3 (HIF PHD1-3) with an IC50 of 1 nM for PHD2.
View activity & pricesDC9835Cytochalasin H
Cytochalasin H is a potent inhibitor of actin incorporation into filaments,a cell-permeable fungal toxin used in actin polymerization studies and cytological research. Cytochalasin H suppresses the production of…
View activity & pricesDC7029SC-26196
SC-26196 is a potent, orally active Delta6 desaturase (D6D) inhibitor (IC50=0.2 µM in a rat liver microsomal assay). Antiinflammatory properties[1].
View activity & pricesDC12443LASV inhibitor 3.3
LASV inhibitor 3.3 (LAMP1 inhibitor 3.3) is a specific inhibitor of Lassa fever virus (LASV, IC50=1.8 uM), inhibits LASV GP-mediated infection and cross-links to the LASV receptor, LAMP1, in cells; does not inhibits…
View activity & pricesDC9287D-Luciferin
D-luciferin is the natural substrate of luciferases that catalyze the production of light in bioluminescent insects.
View activity & pricesDC8783NS 9283
NS9283 is a positive positive allosteric modulator of (α4)3(β2)2 nicotinic ACh receptors. NS9283 can be used in a series of neurological conditions such as attention deficit hyperactivity disorder (ADHD),…
View activity & pricesDC10783PF-9366
PF-9366 is a human methionine adenosyltransferase 2A (Mat2A) inhibitor, with an IC50 of 420 nM and a Kd of 170 nM.
View activity & pricesDC7368AZD5363
Capivasertib (AZD5363) is a potent pan-AKT kinase inhibitor with IC50 of 3, 7 and 7 nM for Akt1,Akt2 and Akt3, respectively.
View activity & pricesDC7553SGC-0946
SGC 0946 is over 100-fold selective For other histone methyltransferases/HMTs. SGC 0946 potently reduces H3K79 dimethylation with IC50 of 2.6 nM in A431 cells, and 8.8 nM in MCF10A cells, which potently and selectively…
View activity & pricesDC21748TG693
TG693 is an orally available, selective, ATP-competitive CLK1 inhibitor with IC50 of 112.6 nM.
View activity & pricesDC10397Proguanil
Proguanil is an antimalarial prodrug that is metabolized to the active metabolite cycloguanil, a dihydrofolate reductase (DHFR) inhibitor.
View activity & pricesDC21695Elamipretide (TFA salt)
Elamipretide is a cardiolipin peroxidase inhibitor and mitochondria-targeting peptide.
View activity & pricesDC7743Mdivi-1
Mdivi-1 is a selective dynamin-related protein 1 (Drp1) inhibitor.
View activity & pricesDC88351-Methoxy PMS
1-Methoxy PMS is stable electron-transport mediator between NAD(P)H and tetrazolium dyes.1-Methoxy PMS can induce active oxygen formation.
View activity & pricesDC23161GDC-0810
GDC-0810 is an orally bioavailable selective estrogen receptor degrader (SERD) with IC50 of 0.7 nM.
View activity & pricesDC30002PF-06835919
PF-06835919, also known as MDK1846, is a potent ketohexokinase (KHK) inhibitor. PF-06835919 is reported in patent US 20170183328 A1, example 4. Increased fructose consumption and its subsequent metabolism have been…
View activity & pricesDC23825BAY-293
BAY-293 is a potent SOS1 inhibitors that block RAS activation via disruption of the RAS-SOS1 interaction with an IC50 of 21 nM[1].
View activity & pricesDC9536Sertindole
Sertindole, a neuroleptic, is one of the newer antipsychotic medications available.In vitro studies showed that sertindole exerts a potent antagonism at serotonin 5-HT2A, 5-HT2C, dopamine D2, and αl adrenergic…
View activity & pricesDC22604Anisomycin
Anisomycin is a potent protein synthesis inhibitor which interferes with protein and DNA synthesis by inhibiting peptidyl transferase or the 80S ribosome system.
View activity & pricesDC10905Exo1
Exo1 is a chemical inhibitor of the exocytic pathway.
View activity & pricesDC5172NLG919(GDC-0919)
IDO-IN-7 (NLG-919 analogue) is a a potent IDO1 inhibitor with an IC50 of 38 nM.
View activity & pricesDC33598GSK-805
GSK805, also known as ROR gamma-t-IN-1, is a potent, orally bioavailable retinoid-related orphan receptor gamma t (RORγt) inverse agonist that interacts with the receptor's putative ligand binding domain without…
View activity & pricesDC7126QNZ(EVP4593)
QNZ shows strong inhibitory effects on NF-κB transcriptional activation and TNF-α production with IC50s of 11 and 7 nM, respectively. EVP4593 is a neuroprotective inhibitor of SOC channel.
View activity & pricesDC10295IPSU
IPSU is a selective, orally available and brain penetrant OX2R antagonist with a pKi of 7.85.
View activity & pricesDC21691SR 8278
SR8278 is a competitive nuclear heme receptor REV-ERB synthetic antagonist. SR8278 inhibits the REV-ERBα transcriptional repression activity with an EC50 of 0.47μM. SR8278 is used to regulate the metabolism in…
View activity & pricesDC8172Lefamulin(BC-3781)
Lefamulin is a semi-synthetic compound that inhibits the synthesis of bacterial protein, which is required for bacteria to grow.
View activity & pricesDC31473Icatibant
Icatibant is a peptidomimetic drug consisting of ten amino acids, which is a selective and specific antagonist of bradykinin B2 receptors. It has been approved by the European Commission for the symptomatic treatment…
View activity & pricesDC43798preQ1 Dihydrochloride
preQ1 is a precursor in the biosynthesis of queuosine, a bacterial nucleoside incorporated into tRNA by tRNA transglycosylase. preQ1 binds to an aptamer domain on tRNA that acts as a riboswitch to repress gene…
View activity & pricesDC10756PF-06291826(Tafamidis)
Tafamidis(Fx1006A) is a potent and selective transthyretin kinetic stabilizer that inhibits the amyloid cascade.Target: OthersTafamidis is a drug for the amelioration of transthyretin-related hereditary…
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