DC21685BVT-948
BVT948 is a protein tyrosine phosphatase (PTP) inhibitor which can also inhibit several cytochrome P450 (P450) isoforms and lysine methyltransferase SETD8.
View activity & pricesDC Chemicals · Research reagentsDC21685 
DC22145
DC51011
DC23748
DC12552
DC51012
DC20311
DC26016
DC22946
DC32472
DCAPI1345
DC9149
DC52032
DC39810
DC53053
DC8013
DCAPI1200
DC8985
DCAPI1398
DC10707
DC9003
DC9249
DC23858
DC33129
DC8953
DC20178
DC10213
DC21101
DC11052
DC20280
DC57071
DC4154
DC57111
DC23147
DC32456
DC20228
DCAPI1056
DCAPI1064
DC21807
DC82030
DC23617
DC21317
DC20890
DC20466
DC7517
DCAPI1372
DC21787
DC39816
Other Research Tools
1099 products · Page 21 of 23
All small molecule research tools
DC21685DC22145MF-766
MF-766 (MF766) is a highly potent and selective EP(4) antagonist with binding Ki of 0.23 nM, displays no significant affinity (>7000-fold selectivity) against other PG receptors (IC50>1500 nM); behaved as a full…
View activity & pricesDC51011IXA6
IXA6 is a novel small molecule compound of inducing IRE1 RNase activity.
View activity & pricesDC23748ML372
ML372 is a small molecule SMN modulator that increases SMN protein in patient fibroblasts with EC50 of 37 nM; possesses good potency, pharmacokinetics, tolerance, and CNS penetration that are able to increase levels of…
View activity & pricesDC12552PGN9856
PGN-9856 (PGN9856) is a novel potent, selective prostaglandin EP2 receptor agonist with pKi of > 8.3, shows higi selectivity over EP1 , EP3 , EP4 , DP, FP, IP and TP receptors; displays a potency (pEC50 >8.5) and a…
View activity & pricesDC51012IXA4
IXA4 is the most selective for the IRE1–XBP1s signaling pathway.IXA4 selectively activate IRE1–XBP1s signaling and reduces secretion of APP through IRE1 activation.
View activity & pricesDC20311Apraglutide
A peptidic glucagon like peptide 2 (GLP-2) analogue for treatment of type2 diabetes.
View activity & pricesDC26016Safinamide mesylate
Safinamide mesylate mesylate (FCE 26743 mesylate; EMD 1195686 mesylate) is a potent, selective, and reversible monoamine oxidase B (MAO-B) inhibitor (IC50=0.098 µM) over MAO-A (IC50=580 µM)[1]. Safinamide mesylate also…
View activity & pricesDC22946ML-T531
ML-T531 is a potent, selective hERG potassium channel (Kv11.1) activator with EC50 of 3.13 uM; exhibits no potentiation for KCNQ1 and KCNE1, and no noticeable effects on other cardiac channels including Cav1.2, Kir2.1,…
View activity & pricesDC32472Zinc Pyrithione
Zinc Pyrithione is a dimer of two pyrithione molecules bound by zinc. It is commonly found as an ingredient of commercial anti-dandruff shampoos. This products acts as an antifungal and antibacterial.
View activity & pricesDCAPI1345Ozagrel HCl
For the detailed information of Ozagrel HCl, the solubility of Ozagrel HCl in water, the solubility of Ozagrel HCl in DMSO, the solubility of Ozagrel HCl in PBS buffer, the animal experiment（test） (test) of Ozagrel…
View activity & pricesDC9149Methotrexate
Methotrexate(WR19039; CL14377) can interfere with the growth of certain cells of the body, especially cells that reproduce quickly, such as cancer cells, bone marrow cells, and skin cells.in vitro: In normal T cells,…
View activity & pricesDC52032Luteolin
Luteolin is a falconoid compound, which exhibits anticancer properties.IC50 value:Target: A natural for anticancer.
View activity & pricesDC39810ICCB-19
ICCB-19 inhibits RIPK1-dependent apoptosis (RDA) with IC50 of 2.01 μM.
View activity & pricesDC53053LGD-3303
LGD-3303 is a selective androgen receptor modulator (SARM).
View activity & pricesDC8013CASIN
CASIN is a selective GTPase Cdc42 inhibitor with IC50 of 2 uM.
View activity & pricesDCAPI1200Estradiol
For the detailed information of Estradiol, the solubility of Estradiol in water, the solubility of Estradiol in DMSO, the solubility of Estradiol in PBS buffer, the animal experiment（test） (test) of Estradiol, the cell…
View activity & pricesDC8985Riluzole
Riluzole is an anticonvulsant drug and belongs to the family of use-dependent Na+ channel blocker which can also inhibit GABA uptake with an IC50 of 43 μM.
View activity & pricesDCAPI1398Disulfiram (Antabuse)
Disulfiram is a specific inhibitor of?aldehyde-dehydrogenase (ALDH1), used for the treatment of chronic alcoholism by producing an acute sensitivity to alcohol.
View activity & pricesDC10707DL-AP4
DL-AP4 (2-Amino-4-phosphonobutyric acid) is a glutamate antagonist. DL-AP4 behaves as a competitive inhibitor of glutamate binding with an apparent Kd of 66 μM. DL-AP4 can be used for the research of central nervous…
View activity & pricesDC9003Triamterene
Triamterene blocks epithelial Na+ channel (ENaC) in a voltage-dependent manner, which used as a mild diuretic.Triamterene blocked rENaC in a voltage-dependent manner, and was 100-fold less potent than amiloride at pH…
View activity & pricesDC92493-Cyano-7-ethoxycoumarin
3-Cyano-7-ethoxycoumarin is a fluorescent P450 substrate (excitation/emission wavelengths = 408/455 nm); metabolized to cyano-hydroxycoumarin.
View activity & pricesDC23858Lanraplenib (GS-9876)
Lanraplenib (GS-9876) is a highly selective and oral SYK inhibitor (IC50=9.5 nM) in development for the treatment of inflammatory diseases. Lanraplenib (GS-9876) inhibits SYK activity in platelets via the glycoprotein…
View activity & pricesDC33129EV-06(Alpha-Lipoic Acid Choline Ester,)
Alpha-Lipoic Acid Choline Ester, also known as alpha-LACE, EV-06 or UNR844, is a drug candidate potentially for the treatment of presbyopia. Alpha-LACE was designed to permeate biological membranes with the…
View activity & pricesDC89536-TG/Thioguanine
6-Thioguanine is an anti-leukemia and immunosuppressant agent, acts as an inhibitor of SARS and MERS coronavirus papain-like proteases (PLpros) and also potently inhibits USP2 activity, with IC50s of 25 μM and 40 μM…
View activity & pricesDC20178Pyrrolidinedithiocarbamate ammonium;APDC, PDTC
Pyrrolidinedithiocarbamate ammonium is a selective NF-κB inhibitor.
View activity & pricesDC10213Fatostatin
Fatostatin hydrobromide (125B11 hydrobromide), a specific inhibitor of SREBP activation, impairs the activation of SREBP-1 and SREBP-2. Fatostatin hydrobromide binds to SCAP (SREBP cleavage-activating protein), and…
View activity & pricesDC21101BDCRB
BDCRB (GW 275175) is a potent and selective inhibitor of human CMV replication by blocking the processing and maturation of viral DNA.
View activity & pricesDC11052GAK inhibitor 12r
GAK inhibitor 12r is a higghly potent, selective inhibitor of cyclin G-associated kinase (GAK) with Kd of 89 nM; targets only 8 other kinases with greater than 90% inhibition in a diverse panel of 468 kinases;…
View activity & pricesDC20280TrkA inhibitor compound 23（TrkA-IN-23）
TrkA-IN-23 is a highly potent, subtype selective, peripherally restricted, allosteric TrkA inhibitor with IC50 of 10 nM, 180-fold selective over TrkB and 70-fold selective over TrkC in cell based assays; exhibits…
View activity & pricesDC57071HB007
HB007 is a small ubiquitin-related modifier 1 (SUMO1) degrader. HB007 induces ubiquitination and degradation of SUMO1, resulting in reduced tumor growth in vivo. HB007 can be used for the research of brain, breast,…
View activity & pricesDC4154Capecitabine
Capecitabine is an oral prodrug that is converted to its active metabolite, fluorouracil (FU), by thymidine phosphorylase.
View activity & pricesDC57111UNC6934
UNC6934 is a potent and selective drug-like chemical probe to interrogate the function of NSD2-PWWP1 with Kd of 91 nM.UNC6934 disrupts the NSD2-PWWP1 interaction with H3K36me2 nucleosomes in U2OS cells as measured by a…
View activity & pricesDC23147Brigatinib (AP-26113)
Brigatinib is a highly potent and selective ALK inhibitor, with an IC50 of 0.6 nM.
View activity & pricesDC32456Pyrinuron
Pyrinuron is an inhibitor of NAMPT and NMNAT2.Pyrinuron is used as a model compound in studies of urea derivatives and their reactivity.Research has explored the effects of this compound on insulin-producing beta…
View activity & pricesDC20228NSC617145(WRN inhibitor)
NSC 617145 is a selective werner syndrome helicase (WRN) helicase inhibitor with an IC50 value of 230 nM. NSC 617145 inhibits WRN ATPase, and induces double-strand breaks (DSB) and chromosomal abnormalities. NSC 617145…
View activity & pricesDCAPI1056Nattokinase
Nattokinase is a potent fibrinolytic enzyme. Nattokinase can break down blood clots by directly hydrolyzing fibrin and plasmin substrate. Nattokinase can be used for the research of cardiovascular diseases[1].
View activity & pricesDCAPI1064mixtures of three isomers (Gentamicins C1, C2, and C1(subA).
Gentamicin sulfate, an aminoglycoside antibiotic, inhibits the growth of both gram-positive and gram-negative bacteria and to inhibit several strains of mycoplasma in tissue culture. It inhibits DNase I with an IC50 of…
View activity & pricesDC21807VU 0465350
A potent, specific BMP receptor activin receptor-like kinase 3 (ALK3) antaognist with Ki of 92.3 nM; shows no activity for ALK2/4/5, also shows affinity for TGFBR2, VEGFR2 and AMPK; blocks SMAD phosphorylation in vitro…
View activity & pricesDC82030MYF-03-176
MYF-03-176 is an orally active and potent anticancer agent. MYF-03-176 shows strong antitumor efficacy in MPM mouse xenograft model via oral administration[1].
View activity & pricesDC23617NAB-14
NAB-14 is a potent, selective negative allosteric modulator of GluN2C/2D-containing NMDA receptors with IC50 of 580 nM, >800-fold selective over GluN2A/GluN2 receptors; inhibits triheteromeric (GluN1/GluN2A/GluN2C)…
View activity & pricesDC21317ML 086 (CID-1674999)
ML 086 is a potent, specific inhibitor of phosphatase PHOSPHO1 with IC50 of 139 nM, with no activity against TNAP (IC50>100 uM); a useful chemical tool to examine the functional role of this enzyme in skeletal…
View activity & pricesDC20890ChoK-α inhibitor CK37
A potent, specific, competitive inhibitor of choline kinase-α (Chok-α) by targeting the choline binding site; significantly increases LC3II expression in MCF-7 and MCF-7/TAM cells, increases the size and number of…
View activity & pricesDC20466MsbA inhibitor 1
MsbA inhibitor 1 is a novel small molecule lipopolysaccharide biogenesis inhibitor, inhibits MsbA, an ATP-dependent flippase that translocates LPS across the inner membrane; causes mislocalization of LPS to the cell…
View activity & pricesDC7517THIACETAZONE
Thiacetazone (Thioacetazone) is a thiourea-containing antitubercular agent and is an orally active antibiotic. Thiacetazone has antibacterial action, which inhibits growth of Mycobacterium tuberculosis H37Rv with a MIC…
View activity & pricesDCAPI1372Ciprofloxacin (Cipro)
Ciprofloxacin is a fluoroquinolone antibiotic, exhibiting potent antibacterial activity.
View activity & pricesDC21787UU-T03
UU-T03 is the ethyl ester derivative of UU-T02, which is a potent, selective inhibitor of β-catenin/Tcf4 interaction with Ki of 1.36 uM; exhibits growth inhibition of SW480 cells with IC50 of 10.77 uM; downregulates…
View activity & pricesDC39816LDC195943(IMT1)
LDC195943(IMT1) is a highly specific inhibitor of human mitochondrial RNA polymerase (POLRMT).
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