DC50013BC1618
BC1618 is a novel Fbxo48 inhibitor and prevent pAmpkα degradation with MEC (minimal efficacious concentration) of 0.6 μM.
View activity & pricesDC Chemicals · Research reagentsDC50013 
DC20558
DC26151
DCC3584
DC48349
DC23481
DC21050
DC20212
DC12668
DC21021
DC12320
DC11818
DC20040
DC8161
DC45040
DC9238
DC60779
DC32224
DC74198
DC66546
DC74177
DC58001
DC11574
DC20244
DC9063
DC22388
DC42673
DC68077
DC21418
DC60778
DC67445
DCAPI1533
DC22431
DC8003
DC74555
DC32195
DCAPI1552
DC10655
DC4156
DC20242
DC20018
DC9625
DC7260
DCAPI1514
DC9810
DC1111
DC7546
DC8356
Other Research Tools
1099 products · Page 22 of 23
All small molecule research tools
DC50013DC20558STOML3 inhibitor OB-1
A small-molecule inhibitor of STOML3 oligomerization that reverses pathological mechanical hypersensitivity in vivo; effectively inhibits the self-association of stomatin, STOML1 and STOML2 at 2 uM, but not podocin;…
View activity & pricesDC26151Naloxone (hydrochloride)
Naloxone is an opioid inverse agonist drug used to counter the effects of opiate overdose.
View activity & pricesDCC3584NCGC00161856
NCGC00161856 is identified as the first small-molecule ligand and inverse agonist of the thyroid-stimulating hormone receptor (TSHR). It inhibits basal cAMP production in HEK-EM 293 cells that stably express TSHRs,…
View activity & pricesDC48349SP-8356
SP-8356, an anti-inflammatory synthetic verbenone derivative, is a potent, orally active cluster of differentiation 147 (CD147) inhibitor. SP-8356 inhibits CD147-cyclophilin A (CypA) interaction and reduces MMP-9…
View activity & pricesDC23481STD-101-D1
STD-101-D1 is a novel brain permeable, G protein-biased beta-1 adrenergic receptor (ADRB1) partial agonist with EC50 of 16.9 nM; engages very little beta-arrestin recruitment compared to the unbiased agonist…
View activity & pricesDC21050FN1-8
FN1-8 is a novel, synthetic small molecule that efficiently interferes with Gli/TAF9 interaction and downregulate Gli/TAF9-dependent transcriptional activity (at 15 uM); inhibits non-canonical Gli activation and acts…
View activity & pricesDC20212Bisphenol A
Bisphenol A is a starting material for the synthesis of plastics, primarily certain polycarbonates and epoxy resins, as well as some polysulfones and certain niche materials. It exhibits estrogen-mimicking,…
View activity & pricesDC12668Citarinostat(ACY-241)
Citarinostat is a HDAC6 specific inhibitor, with IC50 of 4 nM and 76 nM for HDAC6 and HDAC3, respectively.IC50 value: 4 nM (HDAC6), 76 nM (HDAC3)Target: HDACThe detailed information please refer to WO2015061684A1 and…
View activity & pricesDC21021Peptide P60
Peptide P60 (FOXP3 inhibitor P60) is a 15-mer synthetic peptide, cell-permeable inhibitor of FOXP3, binds specifically to FOXP3; inhibits murine and human-derived Treg and improves effector T cell stimulation,…
View activity & pricesDC12320Betanin
In Vitro Betanin is a representative constituent of red beetroot betacyanins, could inhibit peroxynitrite (ONOO-), with an IC50 of 19.2 μM. Betanin also has anti-inflammatory, anti-proliferative effects,…
View activity & pricesDC11818SCB-4380
SCB-4380 (SCB 4380, SCB4380) is the first potent, selective inhibitor for PTPRZ (protein tyrosine phosphatase receptor-type Z) with IC50 of 0.4 uM against human Z-ICR-catalyzed hydrolysis. SCB-4380 also strongly…
View activity & pricesDC20040Trans-Anethole ((E)-Anethole)
Trans-Anethole ((E)-Anethole), a phenylpropene derivative isolated from Pimpinella, shows estrogenic activity at lower concentrations and cytotoxic at higher concentrations in cancer cell lines. Trans-Anethole…
View activity & pricesDC8161Xeglyze(Abametapir)
Abametapir is a metalloproteinase (MMP) inhibitor which is able to target metalloproteinases critical to egg hatching and louse development. Abametapir can inhibit hatching of both head and body louse[1][2].
View activity & pricesDC450402'-O-(2-Methoxyethyl)-uridine
2'-O-(2-Methoxyethyl)-uridine is a synthetic oligonucleotide conversed from uridine. 2'-O-(2-Methoxyethyl)-uridine has the potential for chemotherapeutic agents development.
View activity & pricesDC9238Sancycline
Sancycline is available from DC Chemicals for laboratory research. Contact us for application-specific product information.
View activity & pricesDC60779TH7127
TH7127 is a SAMHD1 inhibitor with IC50 of 4.9 μM/4.5 μM/4.0 μM against dGTP/Cl-F-ara-ATP/ara-CTP, respectively.
View activity & pricesDC32224Nicotinamide riboside
Nicotinamide riboside is a crystal form of Nicotinamide riboside (NR) chloride. Nicotinamide riboside increases NAD[+] levels and activates SIRT1 and SIRT3, culminating in enhanced oxidative metabolism and protection…
View activity & pricesDC74198TMX-4102
TMX-4102 (TMX4102) is a highly potent, selective PIP4K2C binder with KD of 0.45 nM, shows no affinity for PIP4K2B and PIP4K2A (KD>10 uM).
View activity & pricesDC66546R-Sirpiglenastat
R-Sirpiglenastat is the R- isomer of Sirpiglenastat(DRP-104).Sirpiglenastat (DRP104) is a broad acting glutamine antagonist. Sirpiglenastat has anticancer effects by directly targeting tumor metabolism and…
View activity & pricesDC74177SN34960
SN34960 is a small molecule Perforin inhibitor, inhibits perforin-induced lysis of Jurkat T-lymphoma cells with IC50 of 6.65 uM, shows suboptimal physicochemical properties and toxicity toward the natural killer (NK)…
View activity & pricesDC58001BioE-11979（BioE1197）
BioE-1197 is a novel Pask inhibitor. BioE-1197 is a compound that enhances T cell function. Functionally, treatment with BIOE-1197 significantly boosts the ability of effector T cells (such as CD8+, Th1, and Th2 cells)…
View activity & pricesDC11574E3 Ligand-Linker Conjugate 8
An E3 ligase ligand-linker conjugate for PROTAC.
View activity & pricesDC20244ES9-17
ES9-17 is a CME inhibitor a, ES9-17 inhibited recruitment of the plasma membrane-localized BRI1-GFP to the BFA body. Samples were pretreated with 50 µM CHX for 1 h and treated with either DMSO (indicated as Ø) or…
View activity & pricesDC9063Nateglinide
Nateglinide is an insulin secretagog agent used for the treatment of non-insulin-dependent diabetes mellitus (NIDDM).Nateglinide is an oral antihyperglycemic agent used for the treatment of non-insulin-dependent…
View activity & pricesDC22388Mefloquine hydrochloride
A quinoline antimalarial drug that is structurally related to the antiarrhythmic agent quinidine; inhibits autophagy and has been recognized as a potential target for cancer therapy.Bacterial InfectionApproved
View activity & pricesDC42673RS-0406
RS-0406 is a novel beta-sheet breaker, RS-0406 reverses amyloid beta-induced cytotoxicity and impairment of long-term potentiation in vitro. RS-0406 arrests amyloid-beta oligomer-induced behavioural deterioration in…
View activity & pricesDC68077Probe Aca-Bio
Aca-Bio is a specialized chemical probe designed for the specific enrichment and detection of lysine acetoacetylation (Kacac). Its core architecture consists of a hydroxylamine group, a polyethylene glycol (PEG)…
View activity & pricesDC21418NSC 243928
A small molecule that potently inhibit ovarian cancer stem-like cells (CSC) growth with GI50 of 0.83 uM, which os consistent with cell death/apoptosis.
View activity & pricesDC60778TH6342
TH6342 is a SAMHD1 inhibitor with IC50 of 9.1 μM/11.0 μM/5.8 μM against dGTP/Cl-F-ara-ATP/ara-CTP, respectively. TH6342 engages pre-tetrameric SAMHD1 and deter oligomerization and allosteric activation without…
View activity & pricesDC67445LB-102
LB102 demonstrates potent and selective inhibition of PP2A serine/threonine phosphatase activity, with half-maximal inhibitory concentration (IC50) of 400 nM.
View activity & pricesDCAPI1533Piperaquine Phosphate
For the detailed information of Piperaquine Phosphate, the solubility of Piperaquine Phosphate in water, the solubility of Piperaquine Phosphate in DMSO, the solubility of Piperaquine Phosphate in PBS buffer, the…
View activity & pricesDC22431AM432 sodium
AM 432 is potent, selective, orally active prostaglandin D2 receptor (DP2/CRTH2) antagonist with binding IC50 of 6 nM for hDP2; shows no cross-reactivity against the TP or IP receptors, COX-1 or COX-2 and minimal…
View activity & pricesDC8003FRAX486
FRAX486 is a p21-activated kinase (PAK) inhibitor with IC50s of 14, 33 and 39 nM for PAK1, PAK2 and PAK3, respectively.
View activity & pricesDC74555GYS32661
GYS32661 is a potent, small-molecule inhibitor of RAC1 and its isoform RAC1B, specifically designed to target the Sonic Hedgehog (Shh) signaling pathway in cancers like medulloblastoma and colorectal carcinoma.…
View activity & pricesDC32195Benzoyl Peroxide
Benzoyl Peroxide, also known as Bepio and CD-1579, is a bactericidal agent, peroxide derivative that has been used topically for burns and as a dermatologic agent in the treatment of acne and poison ivy dermatitis.…
View activity & pricesDCAPI1552streptomycin
For the detailed information of streptomycin, the solubility of streptomycin in water, the solubility of streptomycin in DMSO, the solubility of streptomycin in PBS buffer, the animal experiment（test） (test) of…
View activity & pricesDC106553-Guanidinopropionic acid
RGX-202 is an oral small-molecule SLC6A8 transporter inhibitor. RGX-202 robustly inhibits creatine import in vitro and in vivo, reduces intracellular phosphocreatine and ATP levels, and induces tumor apoptosis. RGX-202…
View activity & pricesDC4156Tenofovir disoproxil fumarate
For the detailed information about the solubility of Tenofovir disoproxil fumarate in water, the solubility of Tenofovir disoproxil fumarate in DMSO, the solubility of Tenofovir disoproxil fumarate in PBS buffer, the…
View activity & pricesDC20242AZD-7624
AZD7624 is an inhaled p38 inhibitor, with potent anti-inflammatory activity.
View activity & pricesDC20018Enocyanin
In Vitro Enocyanin (0.1%) affects the leucine aminopeptidase, acid phosphatase, γ-glutamyl transpeptidase and esterase activity by 63%, 100%, 134% and 99%, respectively.
View activity & pricesDC9625K145 (hydrochloride)
K145 is a selective SphK2 inhibitor with an IC50 of 4.30±0.06 μM , while no inhibition of SphK1 at concentrations up to 10 μM.IC50 value: 4.3 uM [1]Target: SphK2in vitro: K145 inhibited the activity of SphK2 in a…
View activity & pricesDC7260Reversine
Reversine is a novel class of ATP-competitive Aurora kinase inhibitor with IC50s of 400, 500 and 400 nM for Aurora A, Aurora B and Aurora C, respectively.
View activity & pricesDCAPI1514Micafungin sodium
Micafungin sodium (FK 463) is an antifungal agent which inhibits 1, 3-beta-D-glucan synthesis.
View activity & pricesDC9810ND-646
ND-646 is an orally bioavailable and steric inhibitor of acetyl-CoA carboxylase (ACC) with IC50s of 3.5 nM and 4.1 nM for recombinant hACC1 and hACC2, respectively.
View activity & pricesDC1111UK-5099
UK-5099 is a potent inhibitor of the mitochondrial pyruvate carrier (MPC). UK-5099 ihibits pyruvate-dependent O2 consumption with an IC50 of 50 nM.
View activity & pricesDC7546LHW090-A7 sodium
For the detailed information of LHW090-A7, the solubility of LHW090-A7 in water, the solubility of LHW090-A7 in DMSO, the solubility of LHW090-A7 in PBS buffer, the animal experiment (test) of LHW090-A7, the cell…
View activity & pricesDC8356Losartan Carboxylic Acid
Losartan Carboxylic Acid (E-3174), an active carboxylic acid metabolite of Losartan, is an angiotensin II receptor type 1 (AT1) antagonist. The Ki values are 0.97, 0.57, 0.67 nM for rat AT1B/AT1A and human AT1,…
View activity & prices