XMD-17-51 chemical structure
Chemical structureResearch use only
CAT. NO. DC7688Featured

XMD-17-51

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TotalUS$2,800
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Product overview

Description & Application

XMD-17-51 is a potent NUAK1-specific NUAK1 inhibitor

ParameterValue
Chemical Name5,11-Dihydro-5,11-dimethyl-2-[[1-(4-piperidinyl)-1H-pyrazol-4-yl]amino]-6H-pyrimido[4,5-b][1,4]benzodiazepin-6-one
CAS No.1628614-50-5
SynonymsXMD 17 51, XMD1751
FormulaC21H24N8O
M.Wt404.21
SMILESC1=NC(NC2=CN(C3CCNCC3)N=C2)=NC2N(C)C3C=CC=CC=3C(=O)N(C)C1=2
Purity>98%
Storage2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological Activity

XMD-17-51 is a potent NUAK1-specific NUAK1 inhibitor

In Vitro

XMD-17-51 and XMD-18-42 potently inhibitNUAK1 but not NUAK2, also only partially suppressed MYPT1phosphorylationFor the detailed information about the solubility of XMD-17-51 in water, the solubility of XMD-17-51 in DMSO, the solubility of XMD-17-51 in PBS buffer, the animal experiment of XMD-17-51,the in vivo and in vitro test of XMD-17-51,the cell experiment of XMD-17-51,the IC50 and EC50 of XMD-17-51 please contact DC Chemicals.

In Vivo

No in vivo data are provided in the current product source. Contact us for further information.

References & source

DC Chemicals original product information

Published experimental findings depend on the model and assay conditions. They do not guarantee equivalent performance in every application. For laboratory research use only.

Product documentation

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Handling guide

2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

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