DC Chemicals · Product datasheet

XMD-17-51 — Datasheet

CAT. NO. DC7688

Product page and current package options

ParameterValue
Chemical Name5,11-Dihydro-5,11-dimethyl-2-[[1-(4-piperidinyl)-1H-pyrazol-4-yl]amino]-6H-pyrimido[4,5-b][1,4]benzodiazepin-6-one
CAS No.1628614-50-5
SynonymsXMD 17 51, XMD1751
FormulaC21H24N8O
M.Wt404.21
SMILESC1=NC(NC2=CN(C3CCNCC3)N=C2)=NC2N(C)C3C=CC=CC=3C(=O)N(C)C1=2
Purity>98%
Storage2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological Activity

XMD-17-51 is a potent NUAK1-specific NUAK1 inhibitor

In Vitro

XMD-17-51 and XMD-18-42 potently inhibitNUAK1 but not NUAK2, also only partially suppressed MYPT1phosphorylationFor the detailed information about the solubility of XMD-17-51 in water, the solubility of XMD-17-51 in DMSO, the solubility of XMD-17-51 in PBS buffer, the animal experiment of XMD-17-51,the in vivo and in vitro test of XMD-17-51,the cell experiment of XMD-17-51,the IC50 and EC50 of XMD-17-51 please contact DC Chemicals.

In Vivo

No in vivo data are provided in the current product source. Contact us for further information.

References & source

DC Chemicals original product information

Published experimental findings depend on the model and assay conditions. They do not guarantee equivalent performance in every application. For laboratory research use only.

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