AC-263093 chemical structure
Chemical structureResearch use only
CAT. NO. DC12577Featured

AC-263093

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TotalUS$500
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Product overview

Description & Application

AC-263093 (AC263093) is a potent, functionally selective neuropeptide FF receptor type 2 (NPFFR2) agonist with pKi of 6.9; shows equal affinity for NPFFR1 and NPFFR2, and functionally inactivated NPFFR1; attenuates morphine tolerance in vivo.

ParameterValue
Chemical Name2-[(Z)-(3,4-Dibromophenyl)methylideneamino]guanidine
CAS No.849459-86-5
Synonyms2-[(Z)-(3,4-Dibromophenyl)methylideneamino]guanidine
FormulaC8H8Br2N4
M.Wt319.9839
SMILESBrC1=C(C([H])=C([H])C(/C(/[H])=N\N=C(/N([H])[H])\N([H])[H])=C1[H])Br
Purity>98%
Storage2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological Activity

AC-263093 (AC263093) is a potent, functionally selective neuropeptide FF receptor type 2 (NPFFR2) agonist with pKi of 6.9; shows equal affinity for NPFFR1 and NPFFR2, and functionally inactivated NPFFR1; attenuates morphine tolerance in vivo.

In Vitro

No in vitro data are provided in the current product source. Contact us for further information.

In Vivo

No in vivo data are provided in the current product source. Contact us for further information.

References & source

1. Malin DH, et al. Neurosci Lett. 2015 Jan 1;584:141-5. 2. Lin YT, et al. Exp Neurol. 2017 May;291:62-73. 3. Lin YT, et al. Eur J Pain. 2016 Jul;20(6):895-906. View Related Products by Target Neuropeptide Y Receptor

DC Chemicals original product information

Published experimental findings depend on the model and assay conditions. They do not guarantee equivalent performance in every application. For laboratory research use only.

Product documentation

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Handling guide

2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

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