C12-200
Recommended because it shares a closely related research category or delivery context. Formulation and performance are product- and study-specific.
View product →
Ionizable lipid for LNP and nucleic-acid delivery research.
SM-102 is an ionizable amino lipid that has been used in combination with other lipids in the formation of lipid nanoparticles.Administration of luciferase mRNA in SM-102-containing lipid nanoparticles induces hepatic luciferase expression in mice. Formulations containing SM-102 have been used in the development of lipid nanoparticles for delivery of mRNA-based vaccines.
| CAS No. | Not available |
| Chemical Name | SM-102 |
| Synonyms | SM-102;SM 102;SM102 |
| SMILES | O=C(OC(CCCCCCCC)CCCCCCCC)CCCCCCCN(CCO)CCCCCC(OCCCCCCCCCCC)=O |
| Formula | C44H87NO5 |
| M.Wt | 710.1653 |
| Purity | ELSD-HPLC>95% |
| Storage | Pure form: −20 °C, 1 year; In solvent: −80 °C, 6 months; −20 °C, 1 month. Sealed and protected from light. |
| Shipping condition | Ships from Shanghai. Pure lipid is stable during ice-pack transport. |
| Publication | 1. Sabnis, S., Kumarasinghe , E.S., Salerno, T., et al. A novel amino lipid series for mRNA delivery: Improved endosomal escape and sustained pharmacology and safety in non-human primates. Mol. Ther. 26(6), 1509-1519 (2018). |
The product molecular weight is prefilled when available and remains editable. Confirm solvent compatibility and solubility before preparation.
Solvent volumes update from the molecular weight above.
| Mass | 1 mM | 5 mM | 10 mM |
|---|---|---|---|
| 10 mg | 14.0812 mL | 2.8162 mL | 1.4081 mL |
| 25 mg | 35.2031 mL | 7.0406 mL | 3.5203 mL |
| 50 mg | 70.4061 mL | 14.0812 mL | 7.0406 mL |
| 100 mg | 140.8123 mL | 28.1625 mL | 14.0812 mL |
| 250 mg | 352.0307 mL | 70.4061 mL | 35.2031 mL |
Contact our team with the catalog number and requested quantity.