S-2765(FXa substrate,Z-D-Arg-Gly-Arg-pNA Dihydrochloride) chemical structure
Chemical structureResearch use only
CAT. NO. DC9806Featured

S-2765(FXa substrate,Z-D-Arg-Gly-Arg-pNA Dihydrochloride)

Pack Sizes & Prices

TotalUS$1,500
We match the best price and quality on market.
Product overview

Description & Application

S-2765, which is specific to activated factor X (FXa), is a short peptide covalently bound to pNA (4-nitroaniline). When attacked by FXa, it releases a free pNA which could be detected by a spectrophotometer at 405 nm.S-2765 is mainly used in anti-FXa activity assay of heparin. S-2765 can be used in many applications, such as: 1:Anti-factor Xa activity to anti-factor IIa activity ratios of heparin and LMWHs. 2: Anti-factor Xa activities of heparin and LMWHs. 3: Activities of antithrombin and coagulation factors. 4: Anti-factor Xa activities of heparin and LMWHs in human plasma. 5: Production of kits for automated blood analyzers. 6: Evaluation of potential anticoagulants from chemical synthesis, bacterial fermentation and animal tissues.

ParameterValue
Chemical NameZ-D-Arg-Gly-Arg-pNA Dihydrochloride
CAS No.113711-77-6
SynonymsL-Argininamide,N2-[(phenylmethoxy)carbonyl]-D-arginylglycyl-N-(4-nitrophenyl)-, hydrochloride(1:2);L-Argininamide,N2-[(phenylmethoxy)carbonyl]-D-arginylglycyl-N-(4-nitrophenyl)-, hydrochloride(...;Z-D-ARG-GLY-ARG-PNA · 2 HCL;Chromogenic substrate for thrombin S-2238;Z-D-Arg-Gly-Arg-pNA;S-2765(FXa substrate);Z-D-ARG-GLY-ARG-PNA 2 HCL;L-Argininamide, N2-[(phenylmethoxy)carbonyl]-D-arginylglycyl-N-(4-nitrophenyl)-, hydrochloride (1:2);CID 145710077;Chromogenix S-2238;benzyl N-[(2R)-5-(diaminomethylideneamino)-1-[[2-[[(2S)-5-(diaminomethylideneamino)-1-(4-nitroanilino)-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-1-oxopentan-2-yl]carbamate;CHROMOGENIX;S2765 ;S 2765;Z-D-ARG-GLY-ARG-PNA.2HCL;Z-RGR-PNA
FormulaC28H40ClN11O7
M.Wt678.13970375061
SMILESCl.O=C([C@@H](CCC/N=C(\N)/N)NC(=O)OCC1C=CC=CC=1)NCC(N[C@H](C(NC1C=CC(=CC=1)[N+](=O)[O-])=O)CCC/N=C(\N)/N)=O
Purity>98%
Storage2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological Activity

S-2765, which is specific to activated factor X (FXa), is a short peptide covalently bound to pNA (4-nitroaniline). When attacked by FXa, it releases a free pNA which could be detected by a spectrophotometer at 405 nm.S-2765 is mainly used in anti-FXa activity assay of heparin. S-2765 can be used in many applications, such as: 1:Anti-factor Xa activity to anti-factor IIa activity ratios of heparin and LMWHs. 2: Anti-factor Xa activities of heparin and LMWHs. 3: Activities of antithrombin and coagulation factors. 4: Anti-factor Xa activities of heparin and LMWHs in human plasma. 5: Production of kits for automated blood analyzers. 6: Evaluation of potential anticoagulants from chemical synthesis, bacterial fermentation and animal tissues.

In Vitro

No in vitro data are provided in the current product source. Contact us for further information.

In Vivo

No in vivo data are provided in the current product source. Contact us for further information.

References & source

DC Chemicals original product information

Published experimental findings depend on the model and assay conditions. They do not guarantee equivalent performance in every application. For laboratory research use only.

Product documentation

Refer to the certificate supplied with your lot for batch-specific release results.

Handling guide

2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Solution calculator

Related research products

Coelenterazine chemical structureDC8863

Coelenterazine

Coelenterazine is widely distributed among marine organisms which can produce bioluminescence by calcium-dependent oxidation mediated by the photoprotein aequorin.

View activity & prices
Furimazine chemical structureDC42623

Furimazine

Furimazine is an imidazopyrazinone substrate. NanoLuc (Nluc) paired with Furimazine produced 2.5 million-fold brighter luminescence in mammalian cells relative to Oluc-19 with Coelenterazine.

View activity & prices
AkaLumine chemical structureDC34025

AkaLumine

AkaLumine is a luciferin analogue. The bioluminescence produced by AkaLumine in reactions with native firefly luciferase is in the near-infrared wavelength ranges (λmax=677?nm), and yields significantly increased…

View activity & prices
Hydrofurimazine chemical structureDC45184

Hydrofurimazine

Hydrofurimazine is a NanoLuc substrate whose enhanced aqueous solubility allows delivery of higher doses to mice. Hydrofurimazine enables sensitive bioluminescence imaging for either prolonged light production of high…

View activity & prices
Rhobo6 chemical structureDC67279

Rhobo6

Rhobo6 is a fluorescent glycan-binding probe optimized for live-cell imaging and in vivo tracking of glycoconjugates. It exhibits pH-dependent binding (pKa ~5-7), high photostability, and minimal cytotoxicity.…

View activity & prices
Fluorofurimazine chemical structureDC74576

Fluorofurimazine

Fluorofurimazine is an advanced furimazine derivative with enhanced aqueous solubility, allowing for greater signal output compared to furimazine in bioluminescence imaging. This compound supports higher substrate…

View activity & prices

Cart

Request quotation