CH3OCO-D-CHA-Gly-Arg-pNA (Chromogenic Substrate Pefachrome FXa) chemical structure
Chemical structureResearch use only
CAT. NO. DC53058Featured

CH3OCO-D-CHA-Gly-Arg-pNA (Chromogenic Substrate Pefachrome FXa)

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Product overview

Description & Application

CH3OCO-D-CHA-Gly-Arg-pNA acetate is a chromogenic substrate for factor Xa.

ParameterValue
Chemical NamePEFACHROME(R) FXA*
CAS No.80895-10-9
SynonymsPEFACHROME(R) FXA*;acetic acid,methyl N-[(2R)-3-cyclohexyl-1-[[2-[[(2S)-5-(diaminomethylideneamino)-1-(4-nitroanilino)-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-1-oxopropan-2-yl]carbamate;80895-10-9;80895-10-9;CS-0865277;CS-0865277;Acetic acid--3-cyclohexyl-N-(methoxycarbonyl)-D-alanylglycyl-N~5~-(diaminomethylidene)-N-(4-nitrophenyl)-L-ornithinamide (1/1);Acetic acid--3-cyclohexyl-N-(methoxycarbonyl)-D-alanylglycyl-N~5~-(diaminomethylidene)-N-(4-nitrophenyl)-L-ornithinamide (1/1);Pefachrome(R)fxa*;Pefachrome(R)fxa*;HY-153829;HY-153829;DTXSID30584964;DTXSID30584964;acetic acid;methyl N-[(2R)-3-cyclohexyl-1-[[2-[[(2S)-5-(diaminomethylideneamino)-1-(4-nitroanilino)-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-1-oxopropan-2-yl]carbamate;acetic acid;methyl N-[(2R)-3-cyclohexyl-1-[[2-[[(2S)-5-(diaminomethylideneamino)-1-(4-nitroanilino)-1-oxopentan-2-yl]amino]-2-oxoethyl]amino]-1-oxopropan-2-yl]carbamate;CH3OCO-D-CHA-Gly-Arg-pNA (acetate);CH3OCO-D-CHA-Gly-Arg-pNA (acetate);Pefachrome(R) Fxa, >=95.0% (HPLC);Pefachrome(R) Fxa, >=95.0% (HPLC);CH3OCO-D-CHA-Gly-Arg-pNA acetate
FormulaC27H42N8O9
M.Wt622.670586109161
SMILESCC(=O)O.COC(=O)NC(CC1CCCCC1)C(=O)NCC(=O)NC(CCCN=C(N)N)C(=O)NC2=CC=C(C=C2)[N+](=O)[O-]
Purity>99%
Storage2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological Activity

CH3OCO-D-CHA-Gly-Arg-pNA acetate is a chromogenic substrate for factor Xa.

In Vitro

No in vitro data are provided in the current product source. Contact us for further information.

In Vivo

No in vivo data are provided in the current product source. Contact us for further information.

References & source

Pathology consultation on anticoagulation monitoring: factor X-related assays Wool GD and Lu CM American Journal of Clinical Pathology 140(5), 623-634, (2013) Probing substrate-induced conformational alterations in adrenoleukodystrophy protein by proteolysis Guimaraes CP, et al. Journal of Human Genetics 50(2), 99-99, (2005)Joannsin, a novel Kunitz-type FXa inhibitor from the venom of Prospirobolus joannsi Luan N, et al. Thrombosis and Haemostasis 117(06), 1031-1039, (2017)

DC Chemicals original product information

Published experimental findings depend on the model and assay conditions. They do not guarantee equivalent performance in every application. For laboratory research use only.

Product documentation

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Handling guide

2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Solution calculator

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