E10i-494
Recommended because it shares a closely related research category or delivery context. Formulation and performance are product- and study-specific.
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Ionizable lipid for LNP and nucleic-acid delivery research.
Lipid A6 is an ionizable cationic and biodegradable alkyne lipid (pKa = 6.65).It has been used with other lipids in the formation of lipid nanoparticles (LNPs) for the delivery of mRNA. LNPs containing lipid A6 and encapsulating mRNA encoding human erythropoietin (EPO) increase and then maintain homeostatic levels of hemoglobin in the blood in an adenine-induced mouse model of renal anemia.
| CAS No. | Not available |
| Chemical Name | LIPID A6 |
| Synonyms | A6,LIPID-A6, A-6, A 6 |
| SMILES | N(C)(C)CCCC(=O)OC(CCCCCCCC(=O)OCCC#CCCCCCC)CCCCCCCC(=O)OCCC#CCCCCCC |
| Formula | C43H75NO6 |
| M.Wt | 701.56 |
| Purity | >98% |
| Storage | Pure form: −20 °C, 1 year; In solvent: −80 °C, 6 months; −20 °C, 1 month. Sealed and protected from light. |
| Shipping condition | Ships from Shanghai. Pure lipid is stable during ice-pack transport. |
| Publication | Not available |
The product molecular weight is prefilled when available and remains editable. Confirm solvent compatibility and solubility before preparation.
Solvent volumes update from the molecular weight above.
| Mass | 1 mM | 5 mM | 10 mM |
|---|---|---|---|
| 10 mg | 14.2539 mL | 2.8508 mL | 1.4254 mL |
| 25 mg | 35.6349 mL | 7.1270 mL | 3.5635 mL |
| 50 mg | 71.2697 mL | 14.2539 mL | 7.1270 mL |
| 100 mg | 142.5395 mL | 28.5079 mL | 14.2539 mL |
| 250 mg | 356.3487 mL | 71.2697 mL | 35.6349 mL |
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