E10i-494
Recommended because it shares a closely related research category or delivery context. Formulation and performance are product- and study-specific.
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Ionizable lipid for LNP and nucleic-acid delivery research.
18-2-9b2 is a dendron-like degradable ionizable lipid which facilitates mRNA delivery to splenic macrophages. 18-2-9b2 LNP encapsulating therapeutic BTB domain and CNC homologue 1 (BACH1) mRNA exhibited proficient BACH1 expression and subsequent Spic downregulation in splenic red pulp macrophages (RPM) in a Spic-GFP transgene model.
| CAS No. | Not available |
| Chemical Name | 18-2-9b2 |
| Synonyms | 1829b2, 18 2 9b2 |
| SMILES | CCCCC(CC)CCC(=O)OCC(CC)(COC(=O)CCC(CC)CCCC)COC(=O)CCN(CCOCCN(CCC(=O)OCC(CC)(COC(=O)CCC(CC)CCCC)COC(=O)CCC(CC)CCCC)CCN1CCN(CCOCCN(CCC(=O)OCC(CC)(COC(=O)CCC(CC)CCCC)COC(=O)CCC(CC)CCCC)CCC(=O)OCC(CC)(COC(=O)CCC(CC)CCCC)COC(=O)CCC(CC)CCCC)CC1)CCC(=O)OCC(CC)(COC(=O)CCC(CC)CCCC)COC(=O)CCC(CC)CCCC |
| Formula | C159H293O32N5 |
| M.Wt | 2,787.10 |
| Purity | ELSD-HPLC>95% |
| Storage | Pure form: −20 °C, 1 year; In solvent: −80 °C, 6 months; −20 °C, 1 month. Sealed and protected from light. |
| Shipping condition | Ships from Shanghai. Pure lipid is stable during ice-pack transport. |
| Publication | Not available |
The product molecular weight is prefilled when available and remains editable. Confirm solvent compatibility and solubility before preparation.
Solvent volumes update from the molecular weight above.
| Mass | 1 mM | 5 mM | 10 mM |
|---|---|---|---|
| 10 mg | 3.5880 mL | 717.59 μL | 358.80 μL |
| 25 mg | 8.9699 mL | 1.7940 mL | 896.99 μL |
| 50 mg | 17.9398 mL | 3.5880 mL | 1.7940 mL |
| 100 mg | 35.8796 mL | 7.1759 mL | 3.5880 mL |
| 250 mg | 89.6990 mL | 17.9398 mL | 8.9699 mL |
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