5A2-SC8
Recommended because it shares a closely related research category or delivery context. Formulation and performance are product- and study-specific.
View product →
Ionizable lipid for LNP and nucleic-acid delivery research.
Lipid CAD9 (3-A2-7b is a cationic degradable (CAD) lipid. 3-A2-7b formulated LNP, LNP-CAD9, can deliver FLuc mRNA to the lungs in vivo. LNP-CAD9 co-delivering Cas9 mRNA/VEGFR2 single guide RNA (sgRNA) effectively induces VEGFR2 knock out in lung endothelial cells of female mice.
| CAS No. | Not available |
| Chemical Name | Lipid CAD9 (3-A2-7b) |
| Synonyms | Lipid-CAD9,CAD-9, CAD 9 |
| SMILES | CCCCCC(C)C(=O)OC1=CC(OC(=O)C(C)CCCCC)=CC(CNCCN2CCN(CCNCC3=CC(OC(=O)C(C)CCCCC)=CC(OC(=O)C(C)CCCCC)=C3)CC2)=C1 |
| Formula | C54H88O8N4 |
| M.Wt | 921.32 |
| Purity | 98% |
| Storage | Pure form: −20 °C, 1 year; In solvent: −80 °C, 6 months; −20 °C, 1 month. Sealed and protected from light. |
| Shipping condition | Ships from Shanghai. Pure lipid is stable during ice-pack transport. |
| Publication | High-throughput barcoding of nanoparticles identifies cationic, degradable lipid-like materials for mRNA delivery to the lungs in female preclinical models-Nature Communication-22 January 2024-Lulu Xue,Drew Weissman3,5 & Michael J. Mitchell |
The product molecular weight is prefilled when available and remains editable. Confirm solvent compatibility and solubility before preparation.
Solvent volumes update from the molecular weight above.
| Mass | 1 mM | 5 mM | 10 mM |
|---|---|---|---|
| 10 mg | 10.8540 mL | 2.1708 mL | 1.0854 mL |
| 25 mg | 27.1350 mL | 5.4270 mL | 2.7135 mL |
| 50 mg | 54.2700 mL | 10.8540 mL | 5.4270 mL |
| 100 mg | 108.5399 mL | 21.7080 mL | 10.8540 mL |
| 250 mg | 271.3498 mL | 54.2700 mL | 27.1350 mL |
Contact our team with the catalog number and requested quantity.