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Lipid CAD9 (3-A2-7b)

Version 1.00707146 · 2026-09-13

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CAS No.Not available
Chemical NameLipid CAD9 (3-A2-7b)
SynonymsLipid-CAD9,CAD-9, CAD 9
SMILESCCCCCC(C)C(=O)OC1=CC(OC(=O)C(C)CCCCC)=CC(CNCCN2CCN(CCNCC3=CC(OC(=O)C(C)CCCCC)=CC(OC(=O)C(C)CCCCC)=C3)CC2)=C1
FormulaC54H88O8N4
M.Wt921.32
Purity98%
StorageOriginal product: up to 1 year under the storage conditions stated on the vial, kept tightly sealed. Stock solutions: aliquots at -20°C, generally up to one month.
Shipping conditionShips from Shanghai. Pure lipid is stable during ice-pack transport.
PublicationHigh-throughput barcoding of nanoparticles identifies cationic, degradable lipid-like materials for mRNA delivery to the lungs in female preclinical models-Nature Communication-22 January 2024-Lulu Xue,Drew Weissman3,5 & Michael J. Mitchell

Lipid CAD9 (3-A2-7b is a cationic degradable (CAD) lipid. 3-A2-7b formulated LNP, LNP-CAD9, can deliver FLuc mRNA to the lungs in vivo. LNP-CAD9 co-delivering Cas9 mRNA/VEGFR2 single guide RNA (sgRNA) effectively induces VEGFR2 knock out in lung endothelial cells of female mice.

Specifications shown are product-page values, not batch test results.

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