E10i-494
Recommended because it shares a closely related research category or delivery context. Formulation and performance are product- and study-specific.
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Ionizable lipid for LNP and nucleic-acid delivery research.
Lipid C14-A1 is an ionizable lipid. C14-A1-LPN is a potent and safe LNP platform to deliver Foxp3 mRNA to CD4+ T cells to engineer immunosuppressive FP3T cells.
| CAS No. | Not available |
| Chemical Name | C14-A1 |
| Synonyms | C14A1, C14 A1 |
| SMILES | OC(CN(CC(O)CCCCCCCCCCCC)CCCCCN(CC(CCCCCCCCCCCC)O)CCN1CCN(CCCCCN(CC(O)CCCCCCCCCCCC)CC(CCCCCCCCCCCC)O)CC1)CCCCCCCCCCCC |
| Formula | C86H177N5O5 |
| M.Wt | 1,361.37 |
| Purity | ELSD-HPLC>95% |
| Storage | Pure form: −20 °C, 1 year; In solvent: −80 °C, 6 months; −20 °C, 1 month. Sealed and protected from light. |
| Shipping condition | Ships from Shanghai. Pure lipid is stable during ice-pack transport. |
| Publication | [1]Thatte AS, Hamilton AG, Nachod BE, Mukalel AJ, Billingsley MM, Palanki R, Swingle KL, Mitchell MJ. mRNA Lipid Nanoparticles for Ex Vivo Engineering of Immunosuppressive T Cells for Autoimmunity Therapies. Nano Lett. 2023 Oct 31 |
The product molecular weight is prefilled when available and remains editable. Confirm solvent compatibility and solubility before preparation.
Solvent volumes update from the molecular weight above.
| Mass | 1 mM | 5 mM | 10 mM |
|---|---|---|---|
| 10 mg | 7.3455 mL | 1.4691 mL | 734.55 μL |
| 25 mg | 18.3639 mL | 3.6728 mL | 1.8364 mL |
| 50 mg | 36.7277 mL | 7.3455 mL | 3.6728 mL |
| 100 mg | 73.4554 mL | 14.6911 mL | 7.3455 mL |
| 250 mg | 183.6385 mL | 36.7277 mL | 18.3639 mL |
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