5A2-SC8
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Ionizable lipid for LNP and nucleic-acid delivery research.
93-O17S is an imidazole-based synthetic lipidoid for in vivo mRNA delivery. Lipid nanoparticles (LNPs) with 93-O17S promotes both the cross-presentation of tumor antigens and the intracellular delivery of cGAMP (STING agonist).
| CAS No. | Not available |
| Chemical Name | 93-O17S |
| Synonyms | 93O17S, 93 O17S |
| SMILES | O=C(CCN(CCC(OCCSCCCCCCCCCCCCCC)=O)CCCN1C=NC=C1)OCCSCCCCCCCCCCCCCC |
| Formula | C44H83N3O4S2 |
| M.Wt | 782.3 |
| Purity | ELSD-HPLC>95% |
| Storage | Pure form: −20 °C, 1 year; In solvent: −80 °C, 6 months; −20 °C, 1 month. Sealed and protected from light. |
| Shipping condition | Ships from Shanghai. Pure lipid is stable during ice-pack transport. |
| Publication | 1. Li, Y., Yang, T., Yu, Y., et al. Combinatorial library of chalcogen-containing lipidoids for intracellular delivery of genome-editing proteins. Biomaterials 178, 652-662 (2018). 2. Chen, J., Qiu, M., Ye, Z., et al. In situ cancer vaccination using lipi |
The product molecular weight is prefilled when available and remains editable. Confirm solvent compatibility and solubility before preparation.
Solvent volumes update from the molecular weight above.
| Mass | 1 mM | 5 mM | 10 mM |
|---|---|---|---|
| 10 mg | 12.7828 mL | 2.5566 mL | 1.2783 mL |
| 25 mg | 31.9570 mL | 6.3914 mL | 3.1957 mL |
| 50 mg | 63.9141 mL | 12.7828 mL | 6.3914 mL |
| 100 mg | 127.8282 mL | 25.5656 mL | 12.7828 mL |
| 250 mg | 319.5705 mL | 63.9141 mL | 31.9570 mL |
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