5A2-SC8
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Ionizable lipid for LNP and nucleic-acid delivery research.
9322-O16B is a lipidoid for the efficient delivery of antiCD19 mRNA CAR to murine primary macrophages. LNP 9322-O16B is more efficient than delivery with lipofectamine 2000 (LPF2K) or MC3.
| CAS No. | Not available |
| Chemical Name | 9322-O16B |
| Synonyms | 9322O16B, 9322 O16B |
| SMILES | O=C(CCN(CCC(OCCSSCCCCCCCCCCCC)=O)CCCN1C=CN=C1C)OCCSSCCCCCCCCCCCC |
| Formula | C44H77N3O4S4 |
| M.Wt | 804.3 |
| Purity | ELSD-HPLC>95% |
| Storage | Pure form: −20 °C, 1 year; In solvent: −80 °C, 6 months; −20 °C, 1 month. Sealed and protected from light. |
| Shipping condition | Ships from Shanghai. Pure lipid is stable during ice-pack transport. |
| Publication | Ye, Z., Chen, J., Zhao, X., et al. In vitro engineering chimeric antigen receptor macrophages and T cells by lipid nanoparticle-mediated mRNA delivery. ACS Biomater. Sci. Eng. 8(2), 722-733 (2022). |
The product molecular weight is prefilled when available and remains editable. Confirm solvent compatibility and solubility before preparation.
Solvent volumes update from the molecular weight above.
| Mass | 1 mM | 5 mM | 10 mM |
|---|---|---|---|
| 10 mg | 12.4332 mL | 2.4866 mL | 1.2433 mL |
| 25 mg | 31.0829 mL | 6.2166 mL | 3.1083 mL |
| 50 mg | 62.1659 mL | 12.4332 mL | 6.2166 mL |
| 100 mg | 124.3317 mL | 24.8663 mL | 12.4332 mL |
| 250 mg | 310.8293 mL | 62.1659 mL | 31.0829 mL |
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