DLin-MC3-DMA
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Ionizable lipid for LNP and nucleic-acid delivery research.
DOTAP, also known as 1,2-Dioleoyl-3-trimethylammoniumpropane, is a cationic liposome-forming compound used for transfection of DNA, RNA, and other negatively charged molecules into eukaryotic cells. It has been used in gene delivery vectors for gene ther
| CAS No. | Not available |
| Chemical Name | DOTAP |
| Synonyms | DOTAP; DOTAP chloride; N-(1-(2,3-Dioleoyloxy)propyl)-N,N,N-trimethylammonium chloride; (+/-)-Dotap chloride, DOTAP-Cl |
| SMILES | CCCCCCCC/C=C\CCCCCCCC(OC(C[N+](C)(C)C)COC(CCCCCCC/C=C\CCCCCCCC)=O)=O.[Cl-] |
| Formula | C42H80ClNO4 |
| M.Wt | 698.555 |
| Purity | >98% |
| Storage | Pure form: −20 °C, 1 year; In solvent: −80 °C, 6 months; −20 °C, 1 month. Sealed and protected from light. |
| Shipping condition | Ships from Shanghai. Pure lipid is stable during ice-pack transport. |
| Publication | Not available |
The product molecular weight is prefilled when available and remains editable. Confirm solvent compatibility and solubility before preparation.
Solvent volumes update from the molecular weight above.
| Mass | 1 mM | 5 mM | 10 mM |
|---|---|---|---|
| 10 mg | 14.3153 mL | 2.8631 mL | 1.4315 mL |
| 25 mg | 35.7882 mL | 7.1576 mL | 3.5788 mL |
| 50 mg | 71.5763 mL | 14.3153 mL | 7.1576 mL |
| 100 mg | 143.1527 mL | 28.6305 mL | 14.3153 mL |
| 250 mg | 357.8816 mL | 71.5763 mL | 35.7882 mL |
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