DLin-MC3-DMA
Recommended because it shares a closely related research category or delivery context. Formulation and performance are product- and study-specific.
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Ionizable lipid for LNP and nucleic-acid delivery research.
DLin-KC2-DMA is a highly potent ionizable lipid used in the formulation of lipid nanoparticles (LNPs) for the delivery of siRNA. It represents a significant advancement over earlier generations of lipids, such as DLin-DMA, due to its dramatically improved gene silencing efficiency.
| CAS No. | Not available |
| Chemical Name | DLin-KC2-DMA |
| Synonyms | DLin-KC2-DMA;2,2-dilinoleyl-4-(2-dimethylaminoethyl)-[1,3]-dioxolane;DLinKC2DMA, DLin KC2 DMA |
| SMILES | O1C(CCN(C)C)COC1(CCCCCCCC/C=C\C/C=C\CCCCC)CCCCCCCC/C=C\C/C=C\CCCCC |
| Formula | C43H79NO2 |
| M.Wt | 642.092873811722 |
| Purity | ELSD-HPLC>95% |
| Storage | Pure form: −20 °C, 1 year; In solvent: −80 °C, 6 months; −20 °C, 1 month. Sealed and protected from light. |
| Shipping condition | Ships from Shanghai. Pure lipid is stable during ice-pack transport. |
| Publication | Not available |
The product molecular weight is prefilled when available and remains editable. Confirm solvent compatibility and solubility before preparation.
Solvent volumes update from the molecular weight above.
| Mass | 1 mM | 5 mM | 10 mM |
|---|---|---|---|
| 10 mg | 15.5741 mL | 3.1148 mL | 1.5574 mL |
| 25 mg | 38.9352 mL | 7.7870 mL | 3.8935 mL |
| 50 mg | 77.8704 mL | 15.5741 mL | 7.7870 mL |
| 100 mg | 155.7407 mL | 31.1481 mL | 15.5741 mL |
| 250 mg | 389.3518 mL | 77.8704 mL | 38.9352 mL |
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