Remdesivir(GS-5734) chemical structure
Chemical structureResearch use only
CAT. NO. DC11735Featured

Remdesivir(GS-5734)

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TotalUS$600
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Product overview

Description & Application

Remdesivir(GS-5734) is a nucleoside analogue, with effective antiviral activity, with EC50s of 74 nM for ARS-CoV and MERS-CoV in HAE cells, and 30 nM for murine hepatitis virus in delayed brain tumor cells.

ParameterValue
Chemical NameRemdesivir
CAS No.1809249-37-3
SynonymsGS 5734;GS5734;Remdesivir
FormulaC27H35N6O8P
M.Wt602.58
SMILESC[C@@H](C(=O)OCC(CC)CC)N[P@](=O)(OC[C@@H]1[C@@H](O)[C@@H](O)[C@@](C2N3C(C(=NC=N3)N)=CC=2)(C#N)O1)OC1C=CC=CC=1
Purity>98%
Storage2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological Activity

Remdesivir(GS-5734) is a nucleoside analogue, with effective antiviral activity, with EC50s of 74 nM for ARS-CoV and MERS-CoV in HAE cells, and 30 nM for murine hepatitis virus in delayed brain tumor cells.

In Vitro

Remdesivir (GS-5734) is a potent antiviral agent. Remdesivir inhibits murine hepatitis virus (MHV) with an EC50 of 30 nM, and blocks SARS-CoV and MERS-CoV in HAE cells with EC50s of both 74 nM in HAE cells after treatment for 24 h[1].

In Vivo

No in vivo data are provided in the current product source. Contact us for further information.

References & source

DC Chemicals original product information

Published experimental findings depend on the model and assay conditions. They do not guarantee equivalent performance in every application. For laboratory research use only.

Product documentation

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Handling guide

2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

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