AT-273 chemical structure
Chemical structureResearch use only
CAT. NO. DC53052Featured

AT-273

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TotalUS$450
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Product overview

Description & Application

AT-273 is the nucleoside metabolite of AT-527.

ParameterValue
Chemical NameAT-273
SynonymsAT-273;AT273;AT273
FormulaC11H14FN5O4
M.Wt299.10
SMILESOC[C@@H]1[C@@H](O)[C@H0](F)(C)[C@H](N2C=NC3C(=O)NC(N)=NC=32)O1
Purity>98%
Storage2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological Activity

AT-273 is the nucleoside metabolite of AT-527.

In Vitro

No in vitro data are provided in the current product source. Contact us for further information.

In Vivo

No in vivo data are provided in the current product source. Contact us for further information.

References & source

Berliba E, Bogus M, Vanhoutte F, Berghmans PJ, Good SS, Moussa A, Pietropaolo K, Murphy RL, Zhou XJ, Sommadossi JP. 2019. Safety, pharmacokinetics and antiviral activity of AT-527, a novel purine nucleotide prodrug, in HCV-infected subjects with and without cirrhosis. Antimicrob Agents Chemother 63:e01201-19. https://doi.org/10.1128/AAC.01201-19.

DC Chemicals original product information

Published experimental findings depend on the model and assay conditions. They do not guarantee equivalent performance in every application. For laboratory research use only.

Product documentation

View online datasheetRequest COA / MSDS

Refer to the certificate supplied with your lot for batch-specific release results.

Handling guide

2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Solution calculator

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