4'-fluorouridine (4'-FlU, EIDD-2749) chemical structure
Chemical structureResearch use only
CAT. NO. DC58000Featured

4'-fluorouridine (4'-FlU, EIDD-2749)

Pack Sizes & Prices

TotalUS$700
We match the best price and quality on market.
Product overview

Description & Application

4'-fluorouridine (4'-FlU, EIDD-2749) is a ribonucleoside analog that inhibits respiratory syncytial virus (RSV), related RNA viruses, and SARS-CoV-2 with high selectivity index (EC50/CC50 of ≥1877) in cells and human airway epithelia organoids. 4'-FlU induces a delayed stalling of RSV and SARS-CoV-2 RdRP (RNA-dependent RNA polymerase).

ParameterValue
Chemical Name4'-fluorouridine (4'-FlU, EIDD-2749)
CAS No.1613589-24-4
SynonymsEIDD-2749;EIDD 2749;EIDD2749
FormulaC9H11FN2O6
M.Wt262.19
SMILESO=C1NC(N([C@@H]2O[C@@](CO)(F)[C@@H](O)[C@H]2O)C=C1)=O
Purity>98%
Storage2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological Activity

4'-fluorouridine (4'-FlU, EIDD-2749) is a ribonucleoside analog that inhibits respiratory syncytial virus (RSV), related RNA viruses, and SARS-CoV-2 with high selectivity index (EC50/CC50 of ≥1877) in cells and human airway epithelia organoids. 4'-FlU induces a delayed stalling of RSV and SARS-CoV-2 RdRP (RNA-dependent RNA polymerase).

In Vitro

No in vitro data are provided in the current product source. Contact us for further information.

In Vivo

No in vivo data are provided in the current product source. Contact us for further information.

References & source

DC Chemicals original product information

Published experimental findings depend on the model and assay conditions. They do not guarantee equivalent performance in every application. For laboratory research use only.

Product documentation

View online datasheetRequest COA / MSDS

Refer to the certificate supplied with your lot for batch-specific release results.

Handling guide

2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Solution calculator

Related research products

Mefuparib hydrochloride(CVL218) chemical structureDC20446

Mefuparib hydrochloride(CVL218)

Mefuparib hydrochloride is a potent, highly selective, competitive PARP1/2 inhibitor with IC50 of 3.2/1.9 nM, respectively; displays >406-fold over other major nuclear PARPs including PARP3, TNKS1, TNKS2 and PARP6;…

View activity & prices
Remdesivir(GS-5734) chemical structureDC11735

Remdesivir(GS-5734)

Remdesivir(GS-5734) is a nucleoside analogue, with effective antiviral activity, with EC50s of 74 nM for ARS-CoV and MERS-CoV in HAE cells, and 30 nM for murine hepatitis virus in delayed brain tumor cells.

View activity & prices
AT-527(Bemnifosbuvir hemisulfate) chemical structureDC39024

AT-527(Bemnifosbuvir hemisulfate)

AT-527, a hemisulfate salt of AT-511, a guanosine nucleotide prodrug, is a potent and orally active HCV viral replication inhibitor. AT-527 is highly effective in the control of SARS-CoV-2 (COVID-19) infection in vitro…

View activity & prices
Ensitrelvir (S-217622) chemical structureDC59016

Ensitrelvir (S-217622)

S-217622 is the first oral non-covalent, non-peptidic SARS-CoV-2 3CL protease inhibitor with IC50 of 0.096 μM. S-217622 displays antiviral activity in vitro towards a range of SARS-CoV-2 variants and coronavirus…

View activity & prices

Cart

Request quotation