DC Chemicals · Product datasheet

Remdesivir(GS-5734) — Datasheet

CAT. NO. DC11735

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ParameterValue
Chemical NameRemdesivir
CAS No.1809249-37-3
SynonymsGS 5734;GS5734;Remdesivir
FormulaC27H35N6O8P
M.Wt602.58
SMILESC[C@@H](C(=O)OCC(CC)CC)N[P@](=O)(OC[C@@H]1[C@@H](O)[C@@H](O)[C@@](C2N3C(C(=NC=N3)N)=CC=2)(C#N)O1)OC1C=CC=CC=1
Purity>98%
Storage2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological Activity

Remdesivir(GS-5734) is a nucleoside analogue, with effective antiviral activity, with EC50s of 74 nM for ARS-CoV and MERS-CoV in HAE cells, and 30 nM for murine hepatitis virus in delayed brain tumor cells.

In Vitro

Remdesivir (GS-5734) is a potent antiviral agent. Remdesivir inhibits murine hepatitis virus (MHV) with an EC50 of 30 nM, and blocks SARS-CoV and MERS-CoV in HAE cells with EC50s of both 74 nM in HAE cells after treatment for 24 h[1].

In Vivo

No in vivo data are provided in the current product source. Contact us for further information.

References & source

DC Chemicals original product information

Published experimental findings depend on the model and assay conditions. They do not guarantee equivalent performance in every application. For laboratory research use only.

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