E10i-494
Recommended because it shares a closely related research category or delivery context. Formulation and performance are product- and study-specific.
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Ionizable lipid for LNP and nucleic-acid delivery research.
113-O16B is a disulfide bond-containing ionizable cationic lipidoid. It has been used in the generation of lipid nanoparticles (LNPs) for the delivery of mRNA.
| CAS No. | Not available |
| Chemical Name | 113-O16B |
| Synonyms | 113-O16B,cyclo(Gly-Gln);113O16B, 113 O16B |
| SMILES | N(CCC(=O)OCCSSCCCCCCCCCCCC)(CCC(=O)OCCSSCCCCCCCCCCCC)CCN(C)CCN(CCC(=O)OCCSSCCCCCCCCCCCC)CCC(=O)OCCSSCCCCCCCCCCCC |
| Formula | C73H143N3O8S8 |
| M.Wt | 1,447.45183300972 |
| Purity | ELSD-HPLC>95% |
| Storage | Pure form: −20 °C, 1 year; In solvent: −80 °C, 6 months; −20 °C, 1 month. Sealed and protected from light. |
| Shipping condition | Ships from Shanghai. Pure lipid is stable during ice-pack transport. |
| Publication | Chen, J., Ye, Z., Huang, C., et al. Lipid nanoparticle-mediated lymph node-targeting delivery of mRNA cancer vaccine elicits robust CD8+ T cell response. Proc. Natl. Acad. Sci. USA 119(34), e2207841119 (2022). Chen, J., Ye, Z., Huang, C., et al. Lipid nanoparticle-mediated lymph node-targeting delivery of mRNA cancer vaccine elicits robust CD8+ T cell response. Proc. Natl. Acad. Sci. USA 119(34), e2207841119 (2022). |
The product molecular weight is prefilled when available and remains editable. Confirm solvent compatibility and solubility before preparation.
Solvent volumes update from the molecular weight above.
| Mass | 1 mM | 5 mM | 10 mM |
|---|---|---|---|
| 10 mg | 6.9087 mL | 1.3817 mL | 690.87 μL |
| 25 mg | 17.2717 mL | 3.4543 mL | 1.7272 mL |
| 50 mg | 34.5435 mL | 6.9087 mL | 3.4543 mL |
| 100 mg | 69.0869 mL | 13.8174 mL | 6.9087 mL |
| 250 mg | 172.7173 mL | 34.5435 mL | 17.2717 mL |
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