For research use only. We do not sell to patients.
Ionizable lipids / 93-O17O
93-O17O chemical structure
Product imageResearch use only
CAT. NO. DC82105Featured

93-O17O

Ionizable lipid for LNP and nucleic-acid delivery research.

Pack size & price

USD
TotalUS$450
We match the best price and quality on market.
Ships from ShanghaiIce-pack transportPure lipid recommended
Product overview

Description & Application

93-O17O is a chalcogen-containing ionizable cationic lipidoid. It has been used in the generation of lipid nanoparticles (LNPs). LNPs containing 93-O17O localize to the spleen after intravenous injection into mice.LNPs containing 93-O17O have been used for the delivery of Cre recombinase and ribonucleoproteins for genome editing in mice and for the intratumoral delivery of cGAMP to enhance cross-presentation of tumor antigens.

CAS No.Not available
Chemical Name93-O17O
Synonymsbis(2-(tetradecyloxy)ethyl) 3,3'-((3-(1H-imidazol-1-yl)propyl)azanediyl)dipropionate;93O17O, 93 O17O
SMILESO=C(OCCOCCCCCCCCCCCCCC)CCN(CCCN1C=NC=C1)CCC(OCCOCCCCCCCCCCCCCC)=O
FormulaC44H83N3O6
M.Wt750.2
PurityELSD-HPLC>95%
StoragePure form: −20 °C, 1 year; In solvent: −80 °C, 6 months; −20 °C, 1 month. Sealed and protected from light.
Shipping conditionShips from Shanghai. Pure lipid is stable during ice-pack transport.
Publication1. Zhao, X., Chen, J., Qiu, M., et al. Imidazole-based synthetic lipidoids for in vivo mrna delivery into primary T lymphocytes. Angew. Chem. Int. Ed. Engl. 59(45), 20083-20089 (2020). 2. Chen, J., Qiu, M., Ye, Z., et al. In situ cancer vaccination using lipidoid nanoparticles. Sci. Adv. 7(19), eabf1244 (2021). 3. Li, Y., Yang, T., Yu, Y., et al. Combinatorial library of chalcogen-containing lipidoids for intracellular delivery of genome-editing proteins. Biomaterials 178, 652-662 (2018).
Laboratory planning

Solution Calculators

The product molecular weight is prefilled when available and remains editable. Confirm solvent compatibility and solubility before preparation.

Mass = concentration × volume × molecular weight
Enter any three values to calculate the fourth.
C₁V₁ = C₂V₂
Enter any three values to calculate the fourth.
Preparing stock solutions

Quick preparation table

Solvent volumes update from the molecular weight above.

Mass1 mM5 mM10 mM
10 mg13.3298 mL2.6660 mL1.3330 mL
25 mg33.3244 mL6.6649 mL3.3324 mL
50 mg66.6489 mL13.3298 mL6.6649 mL
100 mg133.2978 mL26.6596 mL13.3298 mL
250 mg333.2445 mL66.6489 mL33.3244 mL

Need a different pack size or technical document?

Contact our team with the catalog number and requested quantity.

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Handling guidance

Shipping, storage and sampling

How is the lipid shipped, and how should I store it?
We generally ship the neat (undissolved) lipid compound rather than an ethanol solution. The neat lipid is stable during transport with ice packs, and shipments originate from Shanghai. Pure form: store at −20 °C for up to 1 year. In solvent: store at −80 °C for up to 6 months or at −20 °C for up to 1 month. Keep sealed and protected from light. Avoid repeated thaw cycles for best results.
Pure lipid or solution — which should I choose?
Pure lipid is generally more stable during shipping and storage, so we usually recommend the pure form. A solution in ethanol or chloroform can be supplied when required by your workflow. Tell us the intended application, solvent and target concentration so the most suitable format can be confirmed.
How should I measure a small amount of oily or viscous lipid?
Ionizable lipids are often oily liquids or viscous semisolids, so material can be lost during repeated weighing or transfer. For a small pack, dissolve the entire quantity and aliquot it volumetrically. For example, add 1 mL ethanol to 25 mg lipid to prepare a 25 mg/mL stock, then use a pipette to withdraw the required amount. For quantities above 100 mg, direct weighing with an analytical balance may be more practical. Always confirm solvent compatibility and solubility first.
Can you support formulation optimization and scale-up?
Yes. Share the RNA cargo, target tissue, administration route, formulation method and assay plan. Our team can discuss starting molar ratios, N/P ratio and scale-up requirements for research workflows.