ALC-0315
Recommended because it shares a closely related research category or delivery context. Formulation and performance are product- and study-specific.
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Ionizable lipid for LNP and nucleic-acid delivery research.
SAL12 is a novel ionizable lipid derivative that integrates a non-nucleotide STING agonist (agonist 6) with an amino lipid tail through an ester bond, forming the core component of specialized lipid nanoparticles (SAL12-LNPs). These nanoparticles are designed for dual functionality: they efficiently encapsulate and deliver mRNA into dendritic cells while concurrently activating the STING pathway to stimulate innate immunity.
| CAS No. | Not available |
| Chemical Name | STING Agonist Lipid SAL-12 |
| Synonyms | STING Agonist Lipid SAL12,SAL-12,SAL 12 |
| SMILES | CCCCCCOCOCCCCCCN(CCCCCCOCOCCCCCC)CCCN(CCCCCCOCOCCCCCC)CCCCCCOC(=O)CCC(=O)C1=CC2=CC(OC)=C(OC)C=C2S1 |
| Formula | C62H112O11N2S |
| M.Wt | 1,093.64 |
| Purity | >98% |
| Storage | Pure form: −20 °C, 1 year; In solvent: −80 °C, 6 months; −20 °C, 1 month. Sealed and protected from light. |
| Shipping condition | Ships from Shanghai. Pure lipid is stable during ice-pack transport. |
| Publication | Not available |
The product molecular weight is prefilled when available and remains editable. Confirm solvent compatibility and solubility before preparation.
Solvent volumes update from the molecular weight above.
| Mass | 1 mM | 5 mM | 10 mM |
|---|---|---|---|
| 10 mg | 9.1438 mL | 1.8288 mL | 914.38 μL |
| 25 mg | 22.8594 mL | 4.5719 mL | 2.2859 mL |
| 50 mg | 45.7189 mL | 9.1438 mL | 4.5719 mL |
| 100 mg | 91.4378 mL | 18.2876 mL | 9.1438 mL |
| 250 mg | 228.5944 mL | 45.7189 mL | 22.8594 mL |
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