E10i-494
Recommended because it shares a closely related research category or delivery context. Formulation and performance are product- and study-specific.
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Ionizable lipid for LNP and nucleic-acid delivery research.
A5-CE-C7-6 (3-tail analog) is a structural control compound derived from the standard 2-tail lipid(A5-CE-C7-6), with three carbonate alkyl chains linked to the A5 amine core.
| CAS No. | Not available |
| Chemical Name | Lipid A5-CE-C7-6(3 tail) |
| Synonyms | Lipid A5 CE C7 6, Lipid A5CEC76 |
| SMILES | CCCCCCC(CCCCCC)OC(=O)OCCN(CCO)CCN(CCOC(=O)OC(CCCCCC)CCCCCC)CCOC(=O)OC(CCCCCC)CCCCCC |
| Formula | C52H102O10N2 |
| M.Wt | 915.39 |
| Purity | >95% by ELSD-HPLC |
| Storage | Pure form: −20 °C, 1 year; In solvent: −80 °C, 6 months; −20 °C, 1 month. Sealed and protected from light. |
| Shipping condition | Ships from Shanghai. Pure lipid is stable during ice-pack transport. |
| Publication | Wu S, Shi L, Su K, Lin L, Yan X, Zhang Y, Gu T, Wang Z, Xu T, Liu S. Carbonate-Bearing Ionizable Lipids for mRNA Delivery to Splenic NK Cells. J Am Chem Soc. 2025 Aug 13;147(32):28665-28673.https://pubs.acs.org/doi/10.1021/jacs.5c01389 |
The product molecular weight is prefilled when available and remains editable. Confirm solvent compatibility and solubility before preparation.
Solvent volumes update from the molecular weight above.
| Mass | 1 mM | 5 mM | 10 mM |
|---|---|---|---|
| 10 mg | 10.9243 mL | 2.1849 mL | 1.0924 mL |
| 25 mg | 27.3108 mL | 5.4622 mL | 2.7311 mL |
| 50 mg | 54.6215 mL | 10.9243 mL | 5.4622 mL |
| 100 mg | 109.2431 mL | 21.8486 mL | 10.9243 mL |
| 250 mg | 273.1076 mL | 54.6215 mL | 27.3108 mL |
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