E10i-494
Recommended because it shares a closely related research category or delivery context. Formulation and performance are product- and study-specific.
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Ionizable lipid for LNP and nucleic-acid delivery research.
cKK-E15 is an ionizable cationic lipid and a derivative of cKK-E12 that has been used in the generation of lipid nanoparticles (LNPs).1 LNPs containing cKK-E15 and encapsulating Cre mRNA induce the expression of Cre in Kupffer cells, endothelial cells, and hepatocytes in Ai14 mice engineered to express the fluorescent protein tdTomato upon translation of Cre.
| CAS No. | Not available |
| Chemical Name | cKK-E15 |
| Synonyms | cKK E15, cKKE15 |
| SMILES | O=C1NC(CCCCN(CC(CCCCCCCCCCCCC)O)CC(CCCCCCCCCCCCC)O)C(NC1CCCCN(CC(CCCCCCCCCCCCC)O)CC(CCCCCCCCCCCCC)O)=O |
| Formula | C72H144N4O6 |
| M.Wt | 1,161.9 |
| Purity | ELSD-HPLC>95% |
| Storage | Pure form: −20 °C, 1 year; In solvent: −80 °C, 6 months; −20 °C, 1 month. Sealed and protected from light. |
| Shipping condition | Ships from Shanghai. Pure lipid is stable during ice-pack transport. |
| Publication | Not available |
The product molecular weight is prefilled when available and remains editable. Confirm solvent compatibility and solubility before preparation.
Solvent volumes update from the molecular weight above.
| Mass | 1 mM | 5 mM | 10 mM |
|---|---|---|---|
| 10 mg | 8.6066 mL | 1.7213 mL | 860.66 μL |
| 25 mg | 21.5165 mL | 4.3033 mL | 2.1516 mL |
| 50 mg | 43.0330 mL | 8.6066 mL | 4.3033 mL |
| 100 mg | 86.0659 mL | 17.2132 mL | 8.6066 mL |
| 250 mg | 215.1648 mL | 43.0330 mL | 21.5165 mL |
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