DMA4-H228
Recommended because it shares a closely related research category or delivery context. Formulation and performance are product- and study-specific.
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Ionizable lipid for LNP and nucleic-acid delivery research.
Lipid I97 is a vitamin B5-derived ionizable lipid for mRNA vaccine delivery. Lipid I97 LNP specifically delivers the mRNA to the spleen and lymph nodes in model mice, induces balanced Th1/Th2 immune responses, and elicits the production of high levels of neutralizing antibodies with low toxicity.
| CAS No. | Not available |
| Chemical Name | Lipid I97 |
| Synonyms | O,O'-((R)-4-((3-(2-(dimethylamino)ethoxy)-3-oxopropyl)amino)-2,2-dimethyl-4-oxobutane-1,3-diyl) bis(2-hexyldecyl) diglutarate;Lipid-I97, I-97, I 97 |
| SMILES | O=C(NCCC(OCCN(C)C)=O)[C@H](OC(CCCC(OCC(CCCCCCCC)CCCCCC)=O)=O)C(C)(COC(CCCC(OCC(CCCCCC)CCCCCCCC)=O)=O)C |
| Formula | C55H102N2O11 |
| M.Wt | 967.4 |
| Purity | >98% |
| Storage | Pure form: −20 °C, 1 year; In solvent: −80 °C, 6 months; −20 °C, 1 month. Sealed and protected from light. |
| Shipping condition | Ships from Shanghai. Pure lipid is stable during ice-pack transport. |
| Publication | Not available |
The product molecular weight is prefilled when available and remains editable. Confirm solvent compatibility and solubility before preparation.
Solvent volumes update from the molecular weight above.
| Mass | 1 mM | 5 mM | 10 mM |
|---|---|---|---|
| 10 mg | 10.3370 mL | 2.0674 mL | 1.0337 mL |
| 25 mg | 25.8425 mL | 5.1685 mL | 2.5842 mL |
| 50 mg | 51.6849 mL | 10.3370 mL | 5.1685 mL |
| 100 mg | 103.3699 mL | 20.6740 mL | 10.3370 mL |
| 250 mg | 258.4246 mL | 51.6849 mL | 25.8425 mL |
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