DC Chemicals — Chemicals for Life Science
← DC60684 product / Instructions for Use
PRODUCT USE GUIDE · DC60684

Lipid I97

Instructions for Use

Download PDFView product

Product information

Lipid I97 is a vitamin B5-derived ionizable lipid for mRNA vaccine delivery. Lipid I97 LNP specifically delivers the mRNA to the spleen and lymph nodes in model mice, induces balanced Th1/Th2 immune responses, and elicits the production of high levels of neutralizing antibodies with low toxicity.

CAS No.Not available
Chemical NameLipid I97
FormulaC55H102N2O11
M.Wt967.4
Purity>98%
StorageOriginal product: up to 1 year under the storage conditions stated on the vial, kept tightly sealed. Stock solutions: aliquots at -20°C, generally up to one month.
Shipping conditionShips from Shanghai. Pure lipid is stable during ice-pack transport.

Formulation & study context

Literature information refers to the cited study and its particular formulation. Administration routes are research context, not clinical instructions or a guarantee of performance.

A complete product-specific formulation has not been verified. No standard ratio is substituted.

N/P ratioNot reported in the verified record
CargoNot available in the verified record
Administration routeNot available in the verified record
Animal modelNot available in the verified record
Formulation processNot available in the verified record

N/P is the molar ratio of specified lipid nitrogen groups to nucleic-acid phosphate groups. A lipid:cargo mass ratio is a different quantity and must not be used as N/P.

Stock-solution preparation table

Calculated from the product-page molecular weight: 967.4 g/mol. Volumes are final solution volumes.

Lipid mass1 mM5 mM10 mM
10 mg10.337 mL2.067 mL1.034 mL
25 mg25.842 mL5.168 mL2.584 mL
50 mg51.685 mL10.337 mL5.168 mL
100 mg103.370 mL20.674 mL10.337 mL
250 mg258.425 mL51.685 mL25.842 mL

Volume (mL) = mass (mg) × 1000 / [MW (g/mol) × concentration (mM)]. These are mathematical conversions, not measured solubility or validated solvent recommendations. Confirm solvent compatibility and the molecular weight of the exact material before use.

Open editable solution calculators →

Handling & storage

Provided that storage conditions are as stated on the product vial and the vial is kept tightly sealed, the product can be stored for up to 1 year.

Wherever possible, prepare and use solutions on the same day. If stock solutions must be prepared in advance, store them as aliquots in tightly sealed vials at -20°C. Generally, these will be usable for up to one month.

Before use, and prior to opening the vial, allow the product to equilibrate to room temperature for at least 1 hour.

References

Not available