E10i-494
Recommended because it shares a closely related research category or delivery context. Formulation and performance are product- and study-specific.
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Ionizable lipid for LNP and nucleic-acid delivery research.
Si6-C14b is a siloxane-incorporated lipid for livertargeting mRNA delivery. The siloxane moieties enhance cellular internalization of mRNA-LNPs and improve their endosomal escape capacity, augmenting their mRNA delivery efficacy.
| CAS No. | Not available |
| Chemical Name | Si6-C14b |
| Synonyms | Si6C14b, Si6 C14b |
| SMILES | CC(C)CCCCCCCCCC(O)CN(CCSCC[Si](C)(C)O[Si](C)(C)CCSCCN(CC(O)CCCCCCCCCC(C)C)CC(O)CCCCCCCCCC(C)C)CC(O)CCCCCCCCCC(C)C |
| Formula | C68H144O5N2S2Si2 |
| M.Wt | 1,190.20 |
| Purity | >98% |
| Storage | Pure form: −20 °C, 1 year; In solvent: −80 °C, 6 months; −20 °C, 1 month. Sealed and protected from light. |
| Shipping condition | Ships from Shanghai. Pure lipid is stable during ice-pack transport. |
| Publication | Not available |
The product molecular weight is prefilled when available and remains editable. Confirm solvent compatibility and solubility before preparation.
Solvent volumes update from the molecular weight above.
| Mass | 1 mM | 5 mM | 10 mM |
|---|---|---|---|
| 10 mg | 8.4019 mL | 1.6804 mL | 840.19 μL |
| 25 mg | 21.0049 mL | 4.2010 mL | 2.1005 mL |
| 50 mg | 42.0097 mL | 8.4019 mL | 4.2010 mL |
| 100 mg | 84.0195 mL | 16.8039 mL | 8.4019 mL |
| 250 mg | 210.0487 mL | 42.0097 mL | 21.0049 mL |
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