C18 NC-TNP
Recommended because it shares a closely related research category or delivery context. Formulation and performance are product- and study-specific.
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Ionizable lipid for LNP and nucleic-acid delivery research.
12T-O14 is a amidine-incorporated degradable (AID) lipid for versatile mRNA delivery. 12T-O14-LNPs mediate efficient intramuscular delivery of mRNA vaccines and systemic delivery of mRNA therapeutics without noticeable toxicity. 12T-O14 serves as a superior supplementary lipid to redirect liver-tropic LNPs to selectively target the lung or spleen via simple adjustment of the formulation.
| CAS No. | Not available |
| Chemical Name | 12T-O14 |
| Synonyms | 12TO14,, 12T O14 |
| SMILES | O=C(CCSCCCC(NC1=CC=C(CCCCCCCCCC)C=C1)=N)OCCCCCCCCCCCCCC |
| Formula | C37H66N2O2S |
| M.Wt | 603.00 |
| Purity | >98% |
| Storage | Pure form: −20 °C, 1 year; In solvent: −80 °C, 6 months; −20 °C, 1 month. Sealed and protected from light. |
| Shipping condition | Ships from Shanghai. Pure lipid is stable during ice-pack transport. |
| Publication | Not available |
The product molecular weight is prefilled when available and remains editable. Confirm solvent compatibility and solubility before preparation.
Solvent volumes update from the molecular weight above.
| Mass | 1 mM | 5 mM | 10 mM |
|---|---|---|---|
| 10 mg | 16.5837 mL | 3.3167 mL | 1.6584 mL |
| 25 mg | 41.4594 mL | 8.2919 mL | 4.1459 mL |
| 50 mg | 82.9187 mL | 16.5837 mL | 8.2919 mL |
| 100 mg | 165.8375 mL | 33.1675 mL | 16.5837 mL |
| 250 mg | 414.5937 mL | 82.9187 mL | 41.4594 mL |
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