PRODUCT DATASHEET · DC60619
12T-O14
Version 1.74bec1b7 · 2026-09-13
| CAS No. | Not available |
| Chemical Name | 12T-O14 |
| Synonyms | 12TO14，， 12T O14 |
| SMILES | O=C(CCSCCCC(NC1=CC=C(CCCCCCCCCC)C=C1)=N)OCCCCCCCCCCCCCC |
| Formula | C37H66N2O2S |
| M.Wt | 603.00 |
| Purity | >98% |
| Storage | Original product: up to 1 year under the storage conditions stated on the vial, kept tightly sealed. Stock solutions: aliquots at -20°C, generally up to one month. |
| Shipping condition | Ships from Shanghai. Pure lipid is stable during ice-pack transport. |
| Publication | Not available |
12T-O14 is a amidine-incorporated degradable (AID) lipid for versatile mRNA delivery. 12T-O14-LNPs mediate efficient intramuscular delivery of mRNA vaccines and systemic delivery of mRNA therapeutics without noticeable toxicity. 12T-O14 serves as a superior supplementary lipid to redirect liver-tropic LNPs to selectively target the lung or spleen via simple adjustment of the formulation.
Specifications shown are product-page values, not batch test results.
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