E10i-494
Recommended because it shares a closely related research category or delivery context. Formulation and performance are product- and study-specific.
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Ionizable lipid for LNP and nucleic-acid delivery research.
TT3 is an ionizable cationic amino lipid that has been used in combination with other lipids in the formation of lipid-like nanoparticles (LLNs). Administration of LLNs containing TT3 and encapsulating mRNA encoding human coagulation Factor IX induces human coagulation Factor IX expression in the plasma of mice.
| CAS No. | Not available |
| Chemical Name | TT3-LLN |
| Synonyms | N1,N3,N5-tris(3-(didocecylamino)propyl)benzene-1,3,5-tricarboxamide,TT-3, TT 3 |
| SMILES | C(C1C=C(C(=O)NCCCN(CCCCCCCCCCCC)CCCCCCCCCCCC)C=C(C(=O)NCCCN(CCCCCCCCCCCC)CCCCCCCCCCCC)C=1)(=O)NCCCN(CCCCCCCCCCCC)CCCCCCCCCCCC |
| Formula | C90H174N6O3 |
| M.Wt | 1,388.38298749924 |
| Purity | >95% |
| Storage | Pure form: −20 °C, 1 year; In solvent: −80 °C, 6 months; −20 °C, 1 month. Sealed and protected from light. |
| Shipping condition | Ships from Shanghai. Pure lipid is stable during ice-pack transport. |
| Publication | Li, B., Luo, X., Deng, B., et al. An orthogonal array optimization of lipid-like nanoparticles for mRNA delivery in vivo. Nano Lett. 15(12), 8099-8107 (2015). |
The product molecular weight is prefilled when available and remains editable. Confirm solvent compatibility and solubility before preparation.
Solvent volumes update from the molecular weight above.
| Mass | 1 mM | 5 mM | 10 mM |
|---|---|---|---|
| 10 mg | 7.2026 mL | 1.4405 mL | 720.26 μL |
| 25 mg | 18.0066 mL | 3.6013 mL | 1.8007 mL |
| 50 mg | 36.0131 mL | 7.2026 mL | 3.6013 mL |
| 100 mg | 72.0262 mL | 14.4052 mL | 7.2026 mL |
| 250 mg | 180.0656 mL | 36.0131 mL | 18.0066 mL |
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