Pexidartinib(PLX3397) chemical structure

Chemical structureResearch use only

CAT. NO. DC8158Featured

Pexidartinib(PLX3397)

Name: Pexidartinib(PLX3397)
Brand: DC Chemicals
SKU: DC8158
Price: 200.0 USD

Pack Sizes & Prices

TotalUS$200

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Product overview

Description & Application

Pexidartinib (PLX-3397) is a multi-targeted receptor tyrosine kinase inhibitor with IC50s of 13 nM, 27 nM, and 11 nM for CSF1R, c-Kit, and FLT3, respectively.

Parameter	Value
Chemical Name	Pexidartinib (PLX3397)
CAS No.	1029044-16-3
Synonyms	PLX3397; PLX-3397; PLX 3397; CML-261; CML 261; CML261; FP-113; FP 113; FP113; Pexidartinib; Turalio
Formula	C20H15ClF3N5
M.Wt	417.81
SMILES	C1=CC(=NC=C1CC2=CNC3=NC=C(C=C23)Cl)NCC4=CN=C(C=C4)C(F)(F)F
Purity	>98%
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological Activity

Pexidartinib (PLX-3397) is a multi-targeted receptor tyrosine kinase inhibitor with IC50s of 13 nM, 27 nM, and 11 nM for CSF1R, c-Kit, and FLT3, respectively.

In Vitro

No in vitro data are provided in the current product source. Contact us for further information.

In Vivo

Pexidartinib is a potent drug for treatment of cancer and used for Phase III TGCT clinical trial[1].

References & source

DC Chemicals original product information

Published experimental findings depend on the model and assay conditions. They do not guarantee equivalent performance in every application. For laboratory research use only.

Product documentation

View online datasheet Request COA / MSDS

Refer to the certificate supplied with your lot for batch-specific release results.

Handling guide

2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Solution calculator

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