Biological Activity
Pexidartinib (PLX-3397) is a multi-targeted receptor tyrosine kinase inhibitor with IC50s of 13 nM, 27 nM, and 11 nM for CSF1R, c-Kit, and FLT3, respectively.
In Vitro
No in vitro data are provided in the current product source. Contact us for further information.
In Vivo
Pexidartinib is a potent drug for treatment of cancer and used for Phase III TGCT clinical trial[1].
References & source
Published experimental findings depend on the model and assay conditions. They do not guarantee equivalent performance in every application. For laboratory research use only.