E10i-494
Recommended because it shares a closely related research category or delivery context. Formulation and performance are product- and study-specific.
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Ionizable lipid for LNP and nucleic-acid delivery research.
9C-SCC-10 is a biodegradable ionizable lipid (pKa 6.42) with a unique crown-like structure, designed for hepatic mRNA delivery. When formulated into lipid nanoparticles (LNPs), it demonstrates selective liver accumulation in murine models, making it particularly suitable for liver-targeted therapeutic applications.
| CAS No. | Not available |
| Chemical Name | 9C-SCC-10 |
| Synonyms | 9CSCC10, 9C SCC 10 ,((((3,3',3''-(1,4,7-triazonane-1,4,7-triyl)tris(propanoyl))tris(oxy))tris(ethane-2,1-diyl))tris(disulfanediyl))tris(ethane-2,1-diyl) tris(3-(decylthio)-2-methylpropanoate) |
| SMILES | CCCCCCCCCCSCC(C(OCCSSCCOC(CCN1CCN(CCN(CCC(OCCSSCCOC(C(CSCCCCCCCCCC)C)=O)=O)CC1)CCC(OCCSSCCOC(C(CSCCCCCCCCCC)C)=O)=O)=O)=O)C |
| Formula | C69H129N3O12S9 |
| M.Wt | 1,481.3 |
| Purity | >98% |
| Storage | Pure form: −20 °C, 1 year; In solvent: −80 °C, 6 months; −20 °C, 1 month. Sealed and protected from light. |
| Shipping condition | Ships from Shanghai. Pure lipid is stable during ice-pack transport. |
| Publication | Not available |
The product molecular weight is prefilled when available and remains editable. Confirm solvent compatibility and solubility before preparation.
Solvent volumes update from the molecular weight above.
| Mass | 1 mM | 5 mM | 10 mM |
|---|---|---|---|
| 10 mg | 6.7508 mL | 1.3502 mL | 675.08 μL |
| 25 mg | 16.8771 mL | 3.3754 mL | 1.6877 mL |
| 50 mg | 33.7541 mL | 6.7508 mL | 3.3754 mL |
| 100 mg | 67.5083 mL | 13.5017 mL | 6.7508 mL |
| 250 mg | 168.7707 mL | 33.7541 mL | 16.8771 mL |
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