Acid-degradable PEG Lipid (ADP-2k)
DC60638
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DMG-PEG 2000 is used for the preparation of liposome for siRNA delivery with improved transfection efficiency in vitro. DMG-PEG 2000 is also used for the lipid nanoparticle for an oral plasmid DNA delivery approach in vivo through a facile surface modification to improve the mucus permeability and delivery efficiency of the nanoparticles1.
| CAS No. | 160743-62-4 |
| Chemical Name | DMG-PEG 2000 |
| Synonyms | Not available |
| SMILES | CCCCCCCCCCCCCC(OC(COCCOC)COC(CCCCCCCCCCCCC)=O)=O.[n] |
| Formula | (C2H4O)NC32H62O5 |
| M.Wt | Not available |
| Purity | >99% |
| Storage | -20°C, protect from light*In solvent : -80°C, 6 months; -20°C, 1 month (protect from light) |
| Shipping condition | Ships from Shanghai; packaging confirmed at order. |
| Publication | 1. Tianqi Nie, et al. Surface Coating Approach to Overcome Mucosal Entrapment of DNA Nanoparticles for Oral Gene Delivery of Glucagon-like Peptide 1.ACS Appl Mater Interfaces. 2019 Aug 21;11(33):29593-29603. |
| Product classification | PEGylated lipids |
The product molecular weight is prefilled when available and remains editable. Confirm solvent compatibility and solubility before preparation.
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