DLin-MC3-DMA
Recommended because it shares a closely related research category or delivery context. Formulation and performance are product- and study-specific.
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Ionizable lipid for LNP and nucleic-acid delivery research.
CL4F11_ζ-2 is an ionizable lipid for hepatic delivery of CRISPR/Cas ribonucleoprotein (RNP). CL4F11_ζ-2 LNP shows an extremely strong inhibitory effect of serum TTR protein levels compared with all the approved ionizable lipids including DLin-MC3-DMA (MC3), SM-102, and ALC-0315.
| CAS No. | Not available |
| Chemical Name | CL4F11-ζ-2 |
| Synonyms | CL4F11ζ2, CL4F11 ζ 2 |
| SMILES | CCCCC(CC)CCCCCC(=O)OCCCCCCC(O)(CCCCCCOC(=O)CCCCCC(CC)CCCC)CCCCN(CCC)CCC |
| Formula | C49H97O5N |
| M.Wt | 780.32 |
| Purity | >98% |
| Storage | Pure form: −20 °C, 1 year; In solvent: −80 °C, 6 months; −20 °C, 1 month. Sealed and protected from light. |
| Shipping condition | Ships from Shanghai. Pure lipid is stable during ice-pack transport. |
| Publication | Not available |
The product molecular weight is prefilled when available and remains editable. Confirm solvent compatibility and solubility before preparation.
Solvent volumes update from the molecular weight above.
| Mass | 1 mM | 5 mM | 10 mM |
|---|---|---|---|
| 10 mg | 12.8153 mL | 2.5631 mL | 1.2815 mL |
| 25 mg | 32.0381 mL | 6.4076 mL | 3.2038 mL |
| 50 mg | 64.0763 mL | 12.8153 mL | 6.4076 mL |
| 100 mg | 128.1526 mL | 25.6305 mL | 12.8153 mL |
| 250 mg | 320.3814 mL | 64.0763 mL | 32.0381 mL |
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