Lipid 35
Recommended because it shares a closely related research category or delivery context. Formulation and performance are product- and study-specific.
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Ionizable lipid for LNP and nucleic-acid delivery research.
H1L1A1B3 is an ionizable lipid which demonstrates a fourfold increase in circRNA transfection efficiency in lung cancer cells over ALC-0315. H1L1A1B31 is capable of proactively stimulating innate immune activation upon injection.
| CAS No. | Not available |
| Chemical Name | H1L1A1B3 |
| Synonyms | 7-(cyclohexylamino)-6-(N-(3-(dimethylamino)propyl)-4-methylnonanamido)-7-oxoheptyl dodecanoate,H1-L1-A1-B3, H1L1A1-B3 |
| SMILES | O=C(C(CCCCCOC(CCCCCCCCCCC)=O)N(CCCN(C)C)C(CCC(C)CCCCC)=O)NC1CCCCC1 |
| Formula | C40H77N3O4 |
| M.Wt | 664.1 |
| Purity | 98% |
| Storage | Pure form: −20 °C, 1 year; In solvent: −80 °C, 6 months; −20 °C, 1 month. Sealed and protected from light. |
| Shipping condition | Ships from Shanghai. Pure lipid is stable during ice-pack transport. |
| Publication | Not available |
The product molecular weight is prefilled when available and remains editable. Confirm solvent compatibility and solubility before preparation.
Solvent volumes update from the molecular weight above.
| Mass | 1 mM | 5 mM | 10 mM |
|---|---|---|---|
| 10 mg | 15.0580 mL | 3.0116 mL | 1.5058 mL |
| 25 mg | 37.6449 mL | 7.5290 mL | 3.7645 mL |
| 50 mg | 75.2899 mL | 15.0580 mL | 7.5290 mL |
| 100 mg | 150.5797 mL | 30.1159 mL | 15.0580 mL |
| 250 mg | 376.4493 mL | 75.2899 mL | 37.6449 mL |
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