E10i-494
Recommended because it shares a closely related research category or delivery context. Formulation and performance are product- and study-specific.
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Ionizable lipid for LNP and nucleic-acid delivery research.
DIM7S is a sugar-alcohol-derived ionizable lipid with mannitol as the precursor. DIM7S LNP is 10-fold, 30-fold, 20-fold, 4-fold and 3-fold superior in mRNA delivery than Lipo 3K, Electro, ALC-0315, MC3 and SM-102, respectively. DIM7S LNP enables effective CD40 mRNA delivery into human peripheral blood monocyte-derived DCs without obvious cytotoxicity.
| CAS No. | Not available |
| Chemical Name | DIM7S |
| Synonyms | Not available |
| SMILES | CCCCCC(CC)OC(=O)CCCCCCCCCN(CCCCCCCCCC(=O)OC(CC)CCCCC)CCCO[C@@H]1CO[C@@H]2[C@H](OCCCN(CCCCCCCCCC(=O)OC(CC)CCCCC)CCCCCCCCCC(=O)OC(CC)CCCCC)CO[C@H]12 |
| Formula | C84H160O12N2 |
| M.Wt | 1,390.21 |
| Purity | 98% |
| Storage | Pure form: −20 °C, 1 year; In solvent: −80 °C, 6 months; −20 °C, 1 month. Sealed and protected from light. |
| Shipping condition | Ships from Shanghai. Pure lipid is stable during ice-pack transport. |
| Publication | Not available |
The product molecular weight is prefilled when available and remains editable. Confirm solvent compatibility and solubility before preparation.
Solvent volumes update from the molecular weight above.
| Mass | 1 mM | 5 mM | 10 mM |
|---|---|---|---|
| 10 mg | 7.1932 mL | 1.4386 mL | 719.32 μL |
| 25 mg | 17.9829 mL | 3.5966 mL | 1.7983 mL |
| 50 mg | 35.9658 mL | 7.1932 mL | 3.5966 mL |
| 100 mg | 71.9316 mL | 14.3863 mL | 7.1932 mL |
| 250 mg | 179.8289 mL | 35.9658 mL | 17.9829 mL |
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