SM-86(Lipid 5)
Recommended because it shares a closely related research category or delivery context. Formulation and performance are product- and study-specific.
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Ionizable lipid for LNP and nucleic-acid delivery research.
MIC1 is a set of multi-charged lipids with four tertiary amino nitrogen atoms (4N4T) which could be constructed and applied to form novel lipid nanoparticles. 4N4T-LNPs based on MIC1 exhibit much higher mRNA translation efficiency than the approved SM-102-LNPs. 4N4T-LNPs are successfully applied to DS mRNA vaccine and the vaccines worked well against SARS-CoV-2 and its variants, including Delta and Omicron.
| CAS No. | Not available |
| Chemical Name | MIC1 |
| Synonyms | N1,N4-bis[2-[bis(2-hydroxytetradecyl)amino]ethyl]-1,4-piperazinedipropanamide |
| SMILES | O=C(NCCN(CC(O)CCCCCCCCCCCC)CC(CCCCCCCCCCCC)O)CCN1CCN(CCC(NCCN(CC(CCCCCCCCCCCC)O)CC(CCCCCCCCCCCC)O)=O)CC1 |
| Formula | C70H142N6O6 |
| M.Wt | 1,163.9 |
| Purity | 98% |
| Storage | Pure form: −20 °C, 1 year; In solvent: −80 °C, 6 months; −20 °C, 1 month. Sealed and protected from light. |
| Shipping condition | Ships from Shanghai. Pure lipid is stable during ice-pack transport. |
| Publication | Not available |
The product molecular weight is prefilled when available and remains editable. Confirm solvent compatibility and solubility before preparation.
Solvent volumes update from the molecular weight above.
| Mass | 1 mM | 5 mM | 10 mM |
|---|---|---|---|
| 10 mg | 8.5918 mL | 1.7184 mL | 859.18 μL |
| 25 mg | 21.4795 mL | 4.2959 mL | 2.1480 mL |
| 50 mg | 42.9590 mL | 8.5918 mL | 4.2959 mL |
| 100 mg | 85.9180 mL | 17.1836 mL | 8.5918 mL |
| 250 mg | 214.7951 mL | 42.9590 mL | 21.4795 mL |
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