Ivacaftor-d9 chemical structure
Chemical structureResearch use onlyView full-size structure
CAT. NO. DC42510Featured

Ivacaftor-d9

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Product overview

Description & Application

Ivacaftor-D9 (CTP-656) is a potent CFTR modulator and exhibits an EC50 value of 255 nM for CFTR potentiation in G551D/F508del HBE Cells. Ivacaftor-D9 acts as an orally active and improved deuterated Ivacaftor analog for cystic fibrosis research.

ParameterValue
Chemical NameIvacaftor-d9
CAS No.1413431-07-8
SynonymsIvacaftor-D9
FormulaC24H19D9N2O3
M.Wt401.55
SMILESCC(C)(C1=CC(C(C([2H])([2H])[2H])(C([2H])([2H])[2H])C([2H])([2H])[2H])=C(C=C1NC(C2=CNC(C=CC=C3)=C3C2=O)=O)O)C
Purity98%
StoragePlease store the product under the recommended conditions in the Certificate of Analysis.

Chemical identity references

Biological Activity

Ivacaftor-D9 (CTP-656) is a potent CFTR modulator and exhibits an EC50 value of 255 nM for CFTR potentiation in G551D/F508del HBE Cells. Ivacaftor-D9 acts as an orally active and improved deuterated Ivacaftor analog for cystic fibrosis research.

In Vitro

No in vitro data are provided in the current product source. Contact us for further information.

In Vivo

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References & source

DC Chemicals original product information

Published experimental findings depend on the model and assay conditions. They do not guarantee equivalent performance in every application. For laboratory research use only.

Product documentation

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Handling guide

Please store the product under the recommended conditions in the Certificate of Analysis.

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