Ivacaftor-d9 Datasheet | DC42510

Ivacaftor-d9 — Datasheet

CAT. NO. DC42510

Parameter	Value
Chemical Name	Ivacaftor-d9
CAS No.	1413431-07-8
Synonyms	Ivacaftor-D9
Formula	C24H19D9N2O3
M.Wt	401.55
SMILES	CC(C)(C1=CC(C(C([2H])([2H])[2H])(C([2H])([2H])[2H])C([2H])([2H])[2H])=C(C=C1NC(C2=CNC(C=CC=C3)=C3C2=O)=O)O)C
Purity	98%
Storage	Please store the product under the recommended conditions in the Certificate of Analysis.

Chemical identity references

Biological Activity

Ivacaftor-D9 (CTP-656) is a potent CFTR modulator and exhibits an EC50 value of 255 nM for CFTR potentiation in G551D/F508del HBE Cells. Ivacaftor-D9 acts as an orally active and improved deuterated Ivacaftor analog for cystic fibrosis research.

In Vitro

No in vitro data are provided in the current product source. Contact us for further information.

In Vivo

No in vivo data are provided in the current product source. Contact us for further information.

References & source

DC Chemicals original product information

Published experimental findings depend on the model and assay conditions. They do not guarantee equivalent performance in every application. For laboratory research use only.