WHI-P258 chemical structure
Chemical structureResearch use only
CAT. NO. DC8080Featured

WHI-P258

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TotalUS$500
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Product overview

Description & Application

WHI-P258, a quinazoline compound, binds to the active site of JAK3 with an estimated Ki of 72 µM. WHI-P258 does not inhibit JAK3 and does not affect the thrombin-induced aggregation of platelets even at 100 μM[1][2].

ParameterValue
Chemical Name6,7-dimethoxy-N-phenylquinazolin-4-amine
CAS No.21561-09-1
SynonymsJAK3 Inhibitor Negative Control,WHIP258,WHI P258
FormulaC16H15N3O2
M.Wt281.31
SMILESCOC1=C(C=C2C(=C1)C(=NC=N2)NC3=CC=CC=C3)OC
Purity>98%
Storage2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological Activity

WHI-P258, a quinazoline compound, binds to the active site of JAK3 with an estimated Ki of 72 µM. WHI-P258 does not inhibit JAK3 and does not affect the thrombin-induced aggregation of platelets even at 100 μM[1][2].

In Vitro

No in vitro data are provided in the current product source. Contact us for further information.

In Vivo

No in vivo data are provided in the current product source. Contact us for further information.

References & source

DC Chemicals original product information

Published experimental findings depend on the model and assay conditions. They do not guarantee equivalent performance in every application. For laboratory research use only.

Product documentation

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Handling guide

2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Solution calculator

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