GalNAc Lipid GL6(GalNAc Lipid 1004)
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Ionizable lipid for LNP and nucleic-acid delivery research.
GalNAc Lipid 1005 is a trivalent GalNAc-lipid conjugate designed for ASGPR-mediated hepatic delivery. It features a lysine-based scaffold covalently linked to three GalNAc moieties via a 44-unit PEG spacer, anchored by a 1,2-O-dioctadecyl-sn-glyceryl (DSG) lipid tail.
| CAS No. | Not available |
| Chemical Name | GalNAc Lipid 1005 |
| Synonyms | GalNAc Lipid-1005 |
| SMILES | CCCCCCCCCCCCCCCCCCOCC(COC(=O)NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(=O)NC(CCCCNC(=O)CCCCOC1OC(CO)C(O)C(O)C1NC(C)=O)C(=O)N(CCCNC(=O)CCCCOC1OC(CO)C(O)C(O)C1NC(C)=O)CCCNC(=O)CCCCOC1OC(CO)C(O)C(O)C1NC(C)=O)OCCCCCCCCCCCCCCCCCC |
| Formula | C184H355O72N9 |
| M.Wt | 3,845.86 |
| Purity | >98% |
| Storage | Pure form: −20 °C, 1 year; In solvent: −80 °C, 6 months; −20 °C, 1 month. Sealed and protected from light. |
| Shipping condition | Ships from Shanghai. Pure lipid is stable during ice-pack transport. |
| Publication | Not available |
The product molecular weight is prefilled when available and remains editable. Confirm solvent compatibility and solubility before preparation.
Solvent volumes update from the molecular weight above.
| Mass | 1 mM | 5 mM | 10 mM |
|---|---|---|---|
| 10 mg | 2.6002 mL | 520.04 μL | 260.02 μL |
| 25 mg | 6.5005 mL | 1.3001 mL | 650.05 μL |
| 50 mg | 13.0010 mL | 2.6002 mL | 1.3001 mL |
| 100 mg | 26.0020 mL | 5.2004 mL | 2.6002 mL |
| 250 mg | 65.0050 mL | 13.0010 mL | 6.5005 mL |
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