Daraxonrasib（RMC-6236） chemical structure
Chemical structureResearch use only
CAT. NO. DC65716Featured

Daraxonrasib（RMC-6236）

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TotalUS$1,600
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Product overview

Description & Application

RAS-IN-2 (Compound A122) is a potent RAS(ON)MULTI inhibitor and can be used for the research of cancer.

ParameterValue
Chemical NameDaraxonrasib（RMC-6236）
CAS No.2765081-21-6
SynonymsRMC6236;RAS-IN-2
FormulaC44H58N8O5S
M.Wt811.046928882599
SMILESC(N1C2=CC=C3C4=CSC(CC(C(=O)N5CCCC(N5)C(=O)OCC(C)(C)CC(C2=C3)=C1C1C=C(N2CCN(C)CC2)C=NC=1C(C)OC)NC(C1CC1C)=O)=N4)C
Purity>99%
Storage2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological Activity

RAS-IN-2 (Compound A122) is a potent RAS(ON)MULTI inhibitor and can be used for the research of cancer.

In Vitro

RAS-IN-2 (Compound A122) (5 days) 抑制 AsPC-1 (K-Ras G12D) 的细胞活力，IC50 为 1-10 μM.

In Vivo

No in vivo data are provided in the current product source. Contact us for further information.

Target

KRas G12D

References & source

[1]. Ethan AHLER, et al. Use of sos1 inhibitors to treat malignancies with shp2 mutations. Patent WO2022060583A1.

DC Chemicals original product information

Published experimental findings depend on the model and assay conditions. They do not guarantee equivalent performance in every application. For laboratory research use only.

Product documentation

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Handling guide

2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

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