Daraxonrasib（RMC-6236） Datasheet | DC65716

Daraxonrasib（RMC-6236） — Datasheet

CAT. NO. DC65716

Parameter	Value
Chemical Name	Daraxonrasib（RMC-6236）
CAS No.	2765081-21-6
Synonyms	RMC6236;RAS-IN-2
Formula	C44H58N8O5S
M.Wt	811.046928882599
SMILES	C(N1C2=CC=C3C4=CSC(CC(C(=O)N5CCCC(N5)C(=O)OCC(C)(C)CC(C2=C3)=C1C1C=C(N2CCN(C)CC2)C=NC=1C(C)OC)NC(C1CC1C)=O)=N4)C
Purity	>99%
Storage	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Biological Activity

RAS-IN-2 (Compound A122) is a potent RAS(ON)MULTI inhibitor and can be used for the research of cancer.

In Vitro

RAS-IN-2 (Compound A122) (5 days) 抑制 AsPC-1 (K-Ras G12D) 的细胞活力，IC50 为 1-10 μM.

In Vivo

No in vivo data are provided in the current product source. Contact us for further information.

Target

KRas G12D

References & source

[1]. Ethan AHLER, et al. Use of sos1 inhibitors to treat malignancies with shp2 mutations. Patent WO2022060583A1.

DC Chemicals original product information

Published experimental findings depend on the model and assay conditions. They do not guarantee equivalent performance in every application. For laboratory research use only.